University College London
London, United Kingdom
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Huntington's disease
FollowWhat is new in Huntington's disease research, which clinical trials are open, and who works on it. From public registries and PubMed, with the source and date of every fact.
Cure status
- PridopidinePhase 3 · NCT07609108
- radiotracer injectionPhase 3 · NCT05808153
- ValbenazinePhase 3 · NCT06312189
- Votoplam (blinded)Phase 3 · NCT07326709
- DeutetrabenazinePhase 2/3 · NCT04713982
- SKY-0515Phase 2/3 · NCT07378644 · NCT07537075 · NCT06873334
- SKY-0515 PlaceboPhase 2/3 · NCT07378644 · NCT06873334
- High doses of Thiamine y BiotinPhase 2 · NCT04478734
- Moderate doses of Thiamine y BiotinPhase 2 · NCT04478734
- NACPhase 2 · NCT05509153
- TominersenPhase 2 · NCT05686551
- VotoplamPhase 2 · NCT06254482
- AB-1001 Gene TherapyPhase 1/2 · NCT05541627
- ER2001 intravenous injectionPhase 1/2 · NCT07339514
- hNSC-01Phase 1/2 · NCT07451613
- intra-striatal rAAV5-miHTTPhase 1/2 · NCT05243017 · NCT04120493
- SPK-10001Phase 1/2 · NCT06826612
- VO659Phase 1/2 · NCT05822908
- [14C] LPM3770164Phase 1 · NCT07516899
- ALN-HTT02Phase 1 · NCT06585449
- RG6496Phase 1 · NCT07246941
- SRP-1005Phase 1 · NCT07536061
- Radioligand [11C]CHDI-00491009Early phase 1 · NCT06634628
Closest to patients
- Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease ProgressionInnovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease ProgressionCommissariat A L'energie Atomique Et Aux Energies Alternatives · Orsay Cedex, France + 1 more hospitalPhase 3Primary completion 2025
- Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's DiseaseStudy of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's DiseaseSkyhawk Therapeutics, Inc. (sponsor) · 12 hospitals in New Zealand and AustraliaPhase 2/3Results expected 2027
- Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington DiseaseImpact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington DiseaseVanderbilt University Medical Center · Nashville, United StatesPhase 2/3Results expected 2027
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Latest news
Results, new trials and publications, newest first. Every item links to its source.
Results and new studies, newest first, in plain words.
Plain-language summary pending. Original title shown.
Publication
Therapeutic Multifaceted Potential of Melatonin in Neurodegenerative Diseases: From Neuroprotective Mechanisms to Translational Promise.
Therapeutic Multifaceted Potential of Melatonin in Neurodegenerative Diseases: From Neuroprotective Mechanisms to Translational Promise.
Current medicinal chemistry
PubMed · PMID 42973361Publication
Early Administration of Methylene Blue Attenuates Mitochondrial Dysfunction and Cognitive Deficits in a Model of Huntington's Disease.
Early Administration of Methylene Blue Attenuates Mitochondrial Dysfunction and Cognitive Deficits in a Model of Huntington's Disease.
Biology
PubMed · PMID 42939402Publication
Evaluation of curcumin as an exploratory pharmacological tool for modulating dysregulated molecular pathways in cellular models of Huntington's disease.
Evaluation of curcumin as an exploratory pharmacological tool for modulating dysregulated molecular pathways in cellular models of Huntington's disease.
Molecular biology reports
PubMed · PMID 42714706
Find fellow researchers
Groups with active Huntington's disease work.
UCL Queen Square Institute of Neurology
London, United Kingdom
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CHDI Foundation
New York, United States
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Inserm
Paris, France
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University of British Columbia
Vancouver, Canada
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Cardiff University
Cardiff, United Kingdom
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Centre National de la Recherche Scientifique
Paris, France
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Harvard University
Cambridge, United States
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Massachusetts General Hospital
Boston, United States
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University of Iowa
Iowa City, United States
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University of Cambridge
Cambridge, United Kingdom
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Johns Hopkins University
Baltimore, United States
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