Target

ACE2

Angiotensin-converting enzyme 2

0open trials
1trial in total
56publications
0researchers

Diseases

Diabetic eye disease1 trial

The last 24 months

New trials, publications, preprints and grants on this target, month by month.

TrialsPublicationsPreprintsGrants

Publication
Angiotensin-(1-7) and ACE2 in maternal obesity: a pathway to protection.
15 Oct 2026· American journal of physiology. Heart and circulatory physiology· PUBMED
Publication
Age-related alterations in the brain ACE2/Ang-(1-7)/Mas receptor axis in normotensive and spontaneously hypertensive rats.
14 Oct 2026· Clinical science (London, England : 1979)· PUBMED
Publication
Metabolic Milieu and Susceptibility: The Combined Benefits of Targeting AMPK and ACE2 for Metabolic Disorders and COVID-19.
11 Oct 2026· International journal of molecular sciences· PUBMED
Publication
Proximal tubule ACE2 mediates early responses to hypertension by regulating intrarenal RAS and sodium homeostasis.
22 Sept 2026· JCI insight· PUBMED
Publication
ACE2 dysregulation and lipid metabolism: Mechanistic interplay between COVID-19 and neurodegeneration.
17 Sept 2026· Molecular aspects of medicine· PUBMED
Publication
ACE2 and Parkinsonism‑related bone metabolic alterations: signaling pathways and hub gene analysis.
9 Sept 2026· Molecular genetics and genomics : MGG· PUBMED
Publication
Correlation between ACE2 and monocrotaline-induced pulmonary arterial hypertension in rats.
9 Sept 2026· Experimental lung research· PUBMED
Publication
ACE2 downregulation contributes to adverse cardiovascular and reproductive outcomes in female mice on high-fat diet.
8 Sept 2026· American journal of physiology. Heart and circulatory physiology· PUBMED
Publication
Mutation-driven structural and functional changes in ACE2 and their potential implications for Alzheimer's disease.
25 Aug 2026· Journal of biomolecular structure & dynamics· PUBMED
Publication
Association of the ACE2 rs879922 Polymorphism with Glaucoma Risk and Serum ACE2 Levels.
8 Aug 2026· Journal of clinical medicine· PUBMED
Publication
Association of ACE2 gene polymorphisms with risk of pulmonary arterial hypertension in neonates with congenital heart disease.
29 Jul 2026· BMC cardiovascular disorders· PUBMED
Publication
Activation of ACE2 by Hazelnut-Derived Peptide YYLLVR: A Novel Strategy against Hypertension-Induced Cognitive Impairment.
29 Jul 2026· Journal of agricultural and food chemistry· PUBMED
Publication
The short ACE2 isoform is upregulated in adipose tissue from women with obesity.
29 Jul 2026· International journal of obesity (2005)· PUBMED
Publication
AMPK/USP10 loop activation of ACE2: implications for pulmonary hypertension.
28 Jul 2026· European heart journal· PUBMED
Publication
Valsartan repurposing to mitigate autoimmune encephalomyelitis via ACE2/Ang1-7/MasR axis pathway cognitive and neuroinflammation modulation; an experimental and chem-bio-informatics study.
15 Jul 2026· European journal of pharmacology· PUBMED
Publication
ACE2 deficiency alters brain RAS signaling to induce pro-inflammatory microglial remodeling and Worsen Parkinson's disease pathology.
8 Jul 2026· Neuroscience· PUBMED
Publication
Influence of inflammatory and reninangiotensin system gene polymorphisms ACE2 rs2285666, IL1A rs1800587, and TNF rs1800629 on COVID-19 severity and the persistence of symptoms in the post-COVID-19 phase: a cross-sectional study.
26 Jun 2026· Einstein (Sao Paulo, Brazil)· PUBMED
Publication
Reduced circulating 20-hydroxyeicosatetraenoic acid and ACE2 in acute coronary syndrome with exploratory cell-based observations.
10 Jun 2026· Scientific reports· PUBMED
Publication
Vascular Immune Crosstalk in COVID-19: RAAS Biomarker Signature Linking Angiotensin II to Respiratory Compromise and Soluble ACE2 to IL-13 and FGF, Revealing Therapeutic Targets.
17 Apr 2026· International journal of molecular sciences· PUBMED
Publication
A synthetic angiotensin II/ACE2-based hormone shunt controlling experimental hypertension.
11 Apr 2026· Nature communications· PUBMED
Publication
Cerebrospinal fluid and frontal cortex TMPRSS2 and ACE2 protein levels differ in Down syndrome and Alzheimer's disease.
9 Apr 2026· Acta neuropathologica communications· PUBMED
Publication
Therapeutic role of miR-296-5p in hypertensive stroke through ACE2-dependent Edn1 suppression.
4 Apr 2026· The International journal of neuroscience· PUBMED
Publication
Targeting C/EBPβ to Suppress Myocardial Fibrosis in Hypertensive Heart Disease: Role of the ACE2/Ang-(1-7) Pathway.
1 Apr 2026· Journal of cellular and molecular medicine· PUBMED
Publication
ACE/ACE2 axis in cardiovascular disease and COVID-19: Molecular insights and therapeutic perspectives.
30 Mar 2026· Journal of cardiovascular and thoracic research· PUBMED
Publication
Does ACE2 deficiency have a role in Parkinson's disease -exacerbated pulmonary fibrosis?
26 Mar 2026· Experimental neurology· PUBMED
Publication
18F‑CC-Omi‑X PET in Characterizing Lipid Metabolism via ACE2 Mapping.
16 Mar 2026· Chemical & biomedical imaging· PUBMED
Publication
Therapeutic Opportunities Targeting the ACE2/Ang-(1-7)/MasR Pathway in Cardiometabolic Disease.
16 Mar 2026· Current hypertension reports· PUBMED
Publication
SARS-CoV-2 antibody-dependent enhancement of infection depends on antibody binding to both ACE2 and Fc receptors.
23 Feb 2026· JCI insight· PUBMED
Publication
Genetic Analysis and Clinical Effect of ACE2 Gene Variants (rs2285666 and rs4646188) on Coronary Syndrome in Dyslipidaemia Patients.
12 Feb 2026· Sultan Qaboos University medical journal· PUBMED
Publication
Broad-spectrum inhibition of SARS-CoV-2 variants by dibutyl phthalate through allosteric disruption of Spike-ACE2 interface.
27 Jan 2026· Frontiers in microbiology· PUBMED

Who works on it

Researchers who published on this target. Leave out your own co-author circle to find people you do not know yet.

No published researcher profile on this target yet.

We look for a fixed list of target names in titles, keywords, intervention names and MeSH terms. A mention does not prove that the work is aimed at that target.

Report an error