Target

BAP1

BRCA1-associated protein 1

5open trials
6trials in total
66publications
0researchers

Diseases

The last 24 months

New trials, publications, preprints and grants on this target, month by month.

TrialsPublicationsPreprintsGrants

Trial
Trial of Temozolomide in BAP1 Mutated Patients With Advanced or Metastatic Cutaneous Melanoma
1 Jun 2027· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publication
Risk estimates in BAP1 tumor predisposition syndrome using the Genotype-Restricted Likelihood (GRL) method.
5 Nov 2026· Genetics in medicine : official journal of the American College of Medical Genetics· PUBMED
Publication
Unveiling molecular signatures in incidentally detected uterine adenomatoid tumors: An immunohistochemical analysis of L1CAM and BAP1.
30 Oct 2026· Indian journal of pathology & microbiology· PUBMED
Publication
BAP1 loss and TFE3 immunoexpression in high-grade clear cell renal cell carcinoma.
24 Oct 2026· Human pathology· PUBMED
Publication
HMGB1 directly activates BAP1 transcription to sustain tumor growth in mesothelioma.
23 Oct 2026· Cell death and differentiation· PUBMED
Publication
Ovarian sex cord-stromal tumors are part of the BAP1-tumor predisposition syndrome: evidence from human carriers and mouse models.
21 Oct 2026· NPJ precision oncology· PUBMED
Publication
Prognostic associations of PD-L1 expression and BAP1 loss in pleural mesothelioma: a retrospective single-center cohort from Colombia.
14 Oct 2026· Frontiers in oncology· PUBMED
Publication
Inhibition of BAP1 Sensitizes Gastric Cancer Cells to 5-Fluorouracil by Promoting BIRC5 Degradation.
8 Oct 2026· Pharmaceuticals (Basel, Switzerland)· PUBMED
Publication
Expanding the clinicopathological spectrum of BAP1 mutated ccRCC: a study of 84 cases in multi-center cohort.
1 Oct 2026· Human pathology· PUBMED
Preprint
BAP1 loss and PRAME expression converge to remodel the tumor-immune ecosystem during uveal melanoma progression.
28 Sept 2026· bioRxiv : the preprint server for biology· PUBMED
Publication
Digital PCR for Detecting Loss of BAP1 and MTAP in Pleural Fluids of Mesothelioma Patients: Perspectives in the Diagnosis.
1 Sept 2026· Pathology international· PUBMED
Publication
Synthesis and biological evaluation of optically active Z250-1659 as a synthetic lethal agent against BAP1-deficient mesothelioma cells.
26 Aug 2026· Bioorganic & medicinal chemistry· PUBMED
Publication
The Prognostic Significance of BRCA1-Associated Protein 1(BAP1) in Malignant Pleural Mesothelioma: A Systematic Review and Meta-Analysis.
24 Jul 2026· Clinical Medicine Insights. Oncology· PUBMED
Publication
Morphologic and Molecular Differences of BAP1 Melanocytomas and BAP1 Inactivated Melanomas.
23 Jul 2026· The American Journal of dermatopathology· PUBMED
Publication
Research progress on the regulation of mesothelioma driven by deubiquitinating enzyme BAP1.
17 Jul 2026· Clinical and experimental medicine· PUBMED
Publication
BAP1 deficiency-induced SKA3 promotes clear cell renal cell carcinoma malignant progression by regulating chromosomal instability.
15 Jul 2026· Cell death & disease· PUBMED
Publication
BAP1 Loss in Pleural Mesothelioma Is Associated With Reduced Soluble CCL2 in Patient Effusion, Abrogated CCL2-Mediated Monocyte Recruitment In Vitro.
10 Jul 2026· JTO clinical and research reports· PUBMED
Publication
Choroidal melanoma and polydactylous onychopapilloma leading to diagnosis of BAP1 tumor predisposition syndrome.
2 Jul 2026· Ophthalmic genetics· PUBMED
Preprint
Clinical phenotypes of uveal melanoma in patients with germline pathogenic/likely pathogenic BAP1 variants.
1 Jul 2026· medRxiv : the preprint server for health sciences· PUBMED
Publication
BAP1 Loss Might Be a Predictive Biomarker for Immunotherapy Response in Pleural Mesothelioma.
1 Jul 2026· Thoracic cancer· PUBMED
Publication
A tailored in vivo CRISPR screen identifies BAP1 as a potent tumor suppressor of sarcoma.
30 Jun 2026· JCI insight· PUBMED
Publication
BAP1 and PBRM1 Loss Is Associated with Aggressive Clinicopathological Features in Clear Cell Renal Cell Carcinoma: Prognostic Implications in a 10-Year Surgical Cohort.
22 Jun 2026· Diagnostics (Basel, Switzerland)· PUBMED
Publication
OGT accelerates diabetic retinopathy via O-GlcNAcylation of BAP1.
9 Jun 2026· Journal of molecular endocrinology· PUBMED
Publication
Base editing reveals context-dependent regulation of adhesion, anoikis, and motility by BAP1 in renal cell models.
2 Jun 2026· Biochemical and biophysical research communications· PUBMED
Publication
Exceptional response of radiotherapy-naïve cranial meningiomas to dual immune checkpoint blockade in BAP1 tumor predisposition syndrome.
20 May 2026· Neuro-oncology advances· PUBMED
Publication
Prognostic value of BAP1 expression in uveal melanoma: a comparative study with histopathological factors in a large Spanish cohort.
13 May 2026· Frontiers in oncology· PUBMED
Publication
Novel CRISPR-Cas9 BAP1 knockout pre-clinical tumor model recapitulates human melanoma tumorigenesis and immune evolution.
5 May 2026· Communications biology· PUBMED
Publication
BAP1 and USP1 cooperate to regulate FANCD2 stability and cell proliferation in mesothelioma cells.
2 May 2026· Cell death & disease· PUBMED
Publication
Melanoma Arising in a BAP1-Inactivated Melanocytic Tumor.
1 May 2026· JAMA dermatology· PUBMED
Publication
Case report: Onychopapilloma in a patient with BAP1 tumor predisposition syndrome-a useful clinical marker?
22 Apr 2026· Familial cancer· PUBMED

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