New trials, publications, preprints and grants on this target, month by month.
Publication
Qi-Blood Harmony Formula mediates post-MI cardioprotection via FTO-driven dual modulation of energy metabolism and fibrosis: a multi-omics validation.
2 Nov 2026· Chinese medicine· PUBMED
Publication
FTO mediated glycolytic metabolism for papillary renal cell carcinoma immune evasion.
31 Oct 2026· Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie· PUBMED
Publication
FTO Dependent Trim14 m6A Modification Regulates Neuroinflammation in MPTP-Induced Parkinson's Disease Models via the RhoA/ROCK Pathway.
30 Oct 2026· Molecular neurobiology· PUBMED
Publication
FTO deficiency mediates ferroptosis to exacerbate cobalt-induced neurotoxicity.
28 Oct 2026· Environmental research· PUBMED
Publication
Discovery of Novel Pyridazine-Containing Nicotinamide Derivatives as Potent FTO Inhibitors for Acute Myeloid Leukemia.
22 Oct 2026· Journal of medicinal chemistry· PUBMED
Publication
Preconditioning induces ischemic tolerance by attenuating ferroptosis: involvement of the m6A-dependent FTO-IGF2BP1/3-ACSL4 regulatory axis.
22 Oct 2026· Neuropharmacology· PUBMED
Publication
Adiposity-related evidence for APOA2, FTO, and MC4R: a PRISMA-ScR scoping review of recent human studies (2019-2025).
19 Oct 2026· Diabetes & metabolic syndrome· PUBMED
Publication
FTO Promotes Osteosarcoma Progression via YAP and Reduces Cisplatin Sensitivity.
15 Oct 2026· Frontiers in bioscience (Landmark edition)· PUBMED
Publication
Mogroside V Promotes Brown Adipose Thermogenesis via FTO-m6A-LETMD1-UCP1 Pathway to Combat Obesity.
11 Oct 2026· Phytotherapy research : PTR· PUBMED
Publication
Hepatic Lipid Stress Drives Metabolic Dysfunction-Associated Steatohepatitis Progression through FTO O-GlcNAcylation-Induced m6A Demethylation of HRAS.
11 Oct 2026· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publication
FTO-Mediated m6A Demethylation in Insulin Resistance and Type 2 Diabetes: Tissue-Specific Mechanisms - a Narrative Review.
8 Oct 2026· Diabetes, metabolic syndrome and obesity : targets and therapy· PUBMED
Publication
Circulating FTO Protein Levels and β-Cell Function in Individuals with Different Metabolic Profiles: A Cross- Sectional Study.
7 Oct 2026· Diabetes, metabolic syndrome and obesity : targets and therapy· PUBMED
Publication
CRISPR screen reveals FTO-mediated m6A modification of ATF3 as protective in ischaemic stroke.
5 Oct 2026· Brain : a journal of neurology· PUBMED
Publication
M6A Demethylase FTO Targets Pcsk9 to Inhibit Vascular Calcification in Chronic Kidney Disease.
1 Oct 2026· Arteriosclerosis, thrombosis, and vascular biology· PUBMED
Publication
FTO mediates benzo[a]pyrene-induced lung cancer progression through regulating ferroptosis via lactylation-driven YTHDF2-KEAP1-NRF2 axis.
29 Sept 2026· Journal of hazardous materials· PUBMED
Publication
Lian-Jia-San-Jie formula suppresses non-small cell lung cancer via FTO-dependent m6A demethylation regulation of lncRNA CASC9 and its downstream CD3EAP.
28 Sept 2026· Biochemistry and biophysics reports· PUBMED
Publication
RNA m6A demethylase FTO in central nervous system disorders: Mechanisms and therapeutic implications.
25 Sept 2026· Progress in neuro-psychopharmacology & biological psychiatry· PUBMED
Publication
FTO/m6A Regulate Prenatal Nicotine-Induced eNOS Uncoupling and BP Susceptibility.
24 Sept 2026· Hypertension (Dallas, Tex. : 1979)· PUBMED
Publication
FTO Mediates the Tobacco Carcinogen NNK-Induced Beas-2B Cells Malignant Transformation via the DIXDC1/PI3K/AKT Signaling Axis.
21 Sept 2026· Chemical research in toxicology· PUBMED
Publication
ADRB3, LEPR, FTO and PPARG variants contribute to obesity-related metabolic syndrome in Brazilian adults: a polygenic risk score approach.
21 Sept 2026· International journal of obesity (2005)· PUBMED
Publication
Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5.
18 Sept 2026· Molecular medicine reports· PUBMED
Publication
FTO-mediated GPX4 m6A modification in ferroptosis-induced DNA damage and inflammatory response during acute lung injury.
16 Sept 2026· Journal of bioenergetics and biomembranes· PUBMED
Publication
FTO-activated DNA walker for specific Na+ imaging in cancer cells.
11 Sept 2026· Chemical communications (Cambridge, England)· PUBMED
Publication
Associations Between FTO (Fat Mass- and Obesity-Associated) Gene Allelic Load and Heart Rate Responses to Submaximal Exercise in Humans: A Cross-Sectional Study.
11 Sept 2026· Biology· PUBMED
Publication
Interactions Between Genetic Risk and Macronutrient Intake on Obesity-Related Traits in Sri Lankan Adults.
9 Sept 2026· Nutrients· PUBMED
Publication
Fat Mass and Obesity Associated (FTO) and Melanocortin 4 Receptor (MC4R) Gene Variants as Prognostic Markers of Obesity in Quetta City.
8 Sept 2026· Genetic testing and molecular biomarkers· PUBMED
Publication
Bone Marrow Mesenchymal Stem Cells Rescue Tendon Injury by Regulating FTO-Mediated m6A Methylation of ELOB.
1 Sept 2026· Journal of biochemical and molecular toxicology· PUBMED
Publication
FTO-Driven m6A Demethylation of TNC Promotes Epithelial-Mesenchymal Transition and Gastric Cancer Metastasis.
31 Aug 2026· Biomedicines· PUBMED
Publication
PFOS-induced mitochondrial ROS impairs male reproductive function by suppressing FTO-dependent m6A RNA demethylation.
26 Aug 2026· The Journal of biological chemistry· PUBMED
Publication
Chronic nitric oxide mediates dual-layer gene regulation through mRNA m6A positional remodeling and parallel transcriptional reprogramming.
16 Aug 2026· Redox biology· PUBMED