New trials, publications, preprints and grants on this target, month by month.
Publication
Modulation of G6PD-mediated Vitamin C Sensitivity in Small Cell Lung Cancer by the AKT/NRF2 axis.
5 Nov 2026· The Journal of biological chemistry· PUBMED
Publication
Targeting PRDX1-G6PD interaction promotes a metabolic vulnerability and redox imbalance in triple-negative breast cancer.
18 Oct 2026· Free radical biology & medicine· PUBMED
Publication
An Eight-Gene Metabolic Prognostic Signature in Head and Neck Squamous Cell Carcinoma: Cross-Cohort Evaluation, Single-Cell Analysis, and Preliminary Functional Evaluation of PYGL and G6PD.
12 Oct 2026· Journal of Cancer· PUBMED
Publication
Inhibition of G6PD-Mediated MAPK Signaling Triggers Mitochondrial Apoptosis and Cell Cycle Arrest in Hepatocellular Carcinoma.
10 Oct 2026· Frontiers in bioscience (Landmark edition)· PUBMED
Publication
lncRNA Gm10451 mediates β-cell functional impairment in type 1 diabetes through the miR-24-3p/G6PD axis.
11 Sept 2026· Endocrine· PUBMED
Publication
HAMP, G6PD, and CCL18 as Potential Molecular Markers to Guide Treatment Decisions in Anti-PD-1/PD-L1 Immunotherapy for Hepatocellular Carcinoma.
31 Aug 2026· Current medicinal chemistry· PUBMED
Publication
Discordantly Low HbA1c in Type 1 Diabetes: Undiagnosed G6PD Deficiency Masking Poor Glycemic Control-A Case Report.
27 Aug 2026· Case reports in endocrinology· PUBMED
Publication
Simultaneous detection of thalassemia, hemoglobinopathies, and G6PD variants using long-read nanopore sequencing: genetic complexity and heterogeneity in Thailand.
11 Aug 2026· PeerJ· PUBMED
Publication
Glycyrrhetinic Acid and Autocrine Motility Factor Converge on G6PD Suppression, Oxidative Stress, and Drug Retention to Impair Pancreatic Ductal Adenocarcinoma Cell Growth.
1 Aug 2026· Anticancer research· PUBMED
Publication
Unexpected Detection of Acute Oxidative Hemolysis Revealing G6PD Deficiency in a Patient With Follicular Lymphoma.
25 Jul 2026· International journal of laboratory hematology· PUBMED
Publication
Lathyrol Targets G6PD to Disrupt Redox Homeostasis in Non-Small Cell Lung Cancer.
20 Jul 2026· ACS omega· PUBMED
Publication
Jack-of-a-new-trade: Itaconate targets the PPP/G6PD to control lung cancer.
7 Jul 2026· Cell metabolism· PUBMED
Publication
Rapid G6PD Screening Workflow for Timely Tumor Lysis Syndrome Management in Pediatric Oncology.
1 Jul 2026· Annals of clinical and laboratory science· PUBMED
Publication
Should Transfusions of Donated G6PD-Deficient Donor Red Blood Cells Be Restricted to Improve Patient Safety? A Critical Review of the Current Literature.
28 Jun 2026· Transfusion medicine reviews· PUBMED
Publication
SUMOylation-stabilized G6PD orchestrates metabolic rewiring for oxidative stress survival and chemoresistance in HCC via a PKCδ-phosphorylation trigger.
26 Jun 2026· Cell death and differentiation· PUBMED
Publication
Gamabufotalin suppresses pancreatic cancer through redox-homeostasis disruption by G6PD downregulation.
18 Jun 2026· Journal of translational medicine· PUBMED
Publication
A Novel Predictive Model Based on Glutathione Metabolism Genes RRM2 and G6PD in Hepatocellular Carcinoma.
16 Jun 2026· Journal of hepatocellular carcinoma· PUBMED
Publication
IRG1/itaconate rewires macrophage and lung tumor metabolism through G6PD inhibition.
3 Jun 2026· Cell metabolism· PUBMED
Publication
RACK1 governs a dual metabolic switch in lung adenocarcinoma through c-Src/G6PD and TRIM21/LDHA Axes.
29 May 2026· Cell death & disease· PUBMED
Publication
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with elevated mean corpuscular volume (MCV) and bilirubin.
11 May 2026· BMC genomic data· PUBMED
Publication
G6PD variants but not Filipino beta-thalassemia are associated with reduced risk of Plasmodium knowlesi infection in Sabah, Malaysia.
15 Apr 2026· Malaria journal· PUBMED
Publication
Acute hemolytic anemia and methemoglobinemia in a pediatric oncology patient with G6PD deficiency: a case report.
13 Apr 2026· Pharmacogenomics· PUBMED
Publication
LncRNA HCP5 remodels G6PD dual post-translational modification to mediate metabolic adaptations driving osimertinib resistance in lung adenocarcinoma.
6 Apr 2026· Journal of advanced research· PUBMED
Publication
When Fever Turns Hemorrhagic in the Maldives: A Case Report of Dengue in a G6PD-Deficient Young Adult With Hemolysis and Rhabdomyolysis.
3 Apr 2026· Case reports in infectious diseases· PUBMED
Publication
The MAFG-AS1/G6PD axis reduces platinum sensitivity in colorectal cancer through pentose phosphate pathway activation.
1 Apr 2026· Journal of translational medicine· PUBMED
Publication
Pseudo-Bartter Syndrome in a Pancreatic Insufficient Infant With CFTR, DNAH9, LYST and G6PD Variants.
1 Apr 2026· Pediatric pulmonology· PUBMED
Publication
RRx-001 inhibits G6PD to deplete NADPH and trigger disulfidptosis coupled with DAMP-mediated immunogenic cell death in hepatocellular carcinoma.
26 Mar 2026· Cell death discovery· PUBMED
Publication
Targeting G6PD (Glucose-6-Phosphate Dehydrogenase) as a Biomarker of Therapeutic Vulnerability in Renal Cell Carcinoma.
20 Mar 2026· International journal of molecular sciences· PUBMED
Publication
Discordantly low HbA1c revealing undiagnosed G6PD deficiency in a patient with type 2 diabetes mellitus.
19 Mar 2026· The American journal of medicine· PUBMED
Publication
Identification of the disulfidptosis-related gene G6PD as a potential biomarker and therapeutic target in pancreatic ductal adenocarcinoma by integrative bioinformatics analysis and experimental validation.
4 Mar 2026· Discover oncology· PUBMED