Target

JNK

c-Jun N-terminal kinase

0open trials
0trials in total
452publications
0researchers

The last 24 months

New trials, publications, preprints and grants on this target, month by month.

TrialsPublicationsPreprintsGrants

Publication
Neryl acetate modulates JNK signaling in streptozotocin-induced diabetic nephropathy.
24 Oct 2026· Tissue & cell· PUBMED
Publication
Xinlikang capsule ameliorates cancer-related fatigue in Lewis lung carcinoma tumor-bearing mice: association with inhibition of oxidative stress and attenuation of JNK activation and bone marrow apoptosis.
23 Oct 2026· Journal of ethnopharmacology· PUBMED
Publication
Combined rituximab and magnesium acetyl taurate therapy attenuates neurodegeneration via ERK/c-JNK/P38MAPK signaling modulation in methylmercury-induced amyotrophic lateral sclerosis-like neurotoxicity.
13 Oct 2026· Naunyn-Schmiedeberg's archives of pharmacology· PUBMED
Publication
De novo MAP2K4 variants cause a neurodevelopmental syndrome and impaired JNK signaling in iPSC-derived neurons.
13 Oct 2026· American journal of human genetics· PUBMED
Publication
TPPU, a soluble epoxide hydrolase inhibitor, mitigates Aβ-induced neurotoxicity via dual modulation of mitochondrial stabilization and JNK suppression.
12 Oct 2026· Biochemistry and biophysics reports· PUBMED
Publication
[The role of the GSTP1/JNK signaling pathway in regulating oxidative stress and programmed cell death in amyotrophic lateral sclerosis].
1 Oct 2026· Zhonghua nei ke za zhi· PUBMED
Publication
A conotoxin-derived peptide exerts anti-tumor effects in ovarian cancer associated with activation of JNK/JunB signaling.
27 Sept 2026· Biochemical pharmacology· PUBMED
Publication
Ethyl caffeate alleviates NAFLD by modulating JNK/IRS-1/AKT signaling and the gut microbiota.
21 Sept 2026· Food & function· PUBMED
Publication
JNK acts as a molecular brake of the CDC73 positive feedback loop to modulate osteosarcoma malignant progression via UBR5.
16 Sept 2026· Oncogene· PUBMED
Publication
(S)-Pyrrolo[1,2-a]pyrazine-3-carboxamide Analogs as Dual Akt/JNK Modulators With Antiproliferative Effects in MDA-MB-468 Cells.
14 Sept 2026· ChemMedChem· PUBMED
Publication
Combination of Chenpi and Banxia alleviates synovial inflammation in a rat model of rheumatoid arthritis by targeting the JNK/AP-1 signaling pathway.
11 Sept 2026· Frontiers in immunology· PUBMED
Publication
Integrative transcriptomic analysis reveals KLHL2 downregulation as a potential driver of microglial inflammation in Alzheimer's disease via the WNK3/JNK/c-Jun axis.
9 Sept 2026· Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics· PUBMED
Publication
Du-Shu-Wan alleviates Tau protein phosphorylation in Alzheimer's disease by regulating MAPK/JNK signaling pathway.
8 Sept 2026· Journal of ethnopharmacology· PUBMED
Publication
Agmatine Sulfate Is Associated with Altered Redox Status, Apoptosis-Associated Responses, and AKT/JNK Signalling in Ishikawa Endometrial Cancer Cells.
5 Sept 2026· Life (Basel, Switzerland)· PUBMED
Publication
Differential Modulation of the DR5-JNK-PD-L1 Signaling Axis by TRiC/CCT Subunits CCT7 and CCT2 Shapes Tumor Immune Evasion in Lung Adenocarcinoma.
4 Sept 2026· Cells· PUBMED
Publication
Interleukin13 Ameliorates Hepatocellular Steatosis via IL13Rα1/JNK/FOSL2 Signaling Pathway.
3 Sept 2026· Cellular and molecular gastroenterology and hepatology· PUBMED
Publication
[Mechanism of gypenoside LI inducing apoptosis and autophagy in clear cell renal cell carcinoma cells via ROS/JNK and Akt/mTOR signaling pathways].
1 Sept 2026· Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica· PUBMED
Publication
Angiopoietin-Like 4 Induces Upregulation of VEGF and sVCAM1 Through JNK/c-Jun and JAK2/STAT5 Signaling Pathways.
1 Sept 2026· Investigative ophthalmology & visual science· PUBMED
Publication
Targeting Insulin Signaling and TRAF2/JNK Pathway: A Comprehensive In Silico Study of Uncaria tomentosa Compounds.
28 Aug 2026· International journal of molecular sciences· PUBMED
Publication
FMRP promotes gastric cancer progression via m6A-dependent stabilization of DVL2 and activation of the Wnt/PCP-JNK pathway.
22 Aug 2026· Journal of translational medicine· PUBMED
Publication
Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.
19 Aug 2026· Proceedings of the National Academy of Sciences of the United States of America· PUBMED
Publication
Lyoniresinol Improves Insulin Sensitivity and Induces White-to-Beige Adipose Tissue Conversion in Obese Rats: Associated with JNK/PI3K/mTOR Pathway Modulation.
19 Aug 2026· Iranian journal of pharmaceutical research : IJPR· PUBMED
Publication
Norcantharidin induces apoptosis in hepatocellular carcinoma MHCC97-H cells in association with altered NF-κB/IκBα signaling dynamics and JNK activation.
15 Aug 2026· American journal of translational research· PUBMED
Publication
α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model.
14 Aug 2026· International journal of molecular medicine· PUBMED
Publication
Diabetic and ER-stressed pancreatic islet β cells are in need of some JNK removal.
3 Aug 2026· The Journal of clinical investigation· PUBMED
Publication
JNK and p53 cause human and mouse β cell death during excessive unfolded protein response.
3 Aug 2026· The Journal of clinical investigation· PUBMED
Publication
β3-AR/β-arrestin2 Interaction Triggers Cardiac Fibrosis Through JNK/c-Jun Pathway in Cardiac Fibroblasts.
1 Aug 2026· Journal of cellular and molecular medicine· PUBMED
Publication
Qingda Granule and Its Individual Herbs Inhibit Hypertension-Induced Vascular Smooth Muscle Cells Proliferation via ERK and JNK Pathways.
31 Jul 2026· Chinese journal of integrative medicine· PUBMED
Publication
SOX9 knockdown alleviates Aβ1‑42‑induced neuroinflammation by regulating microglial polarization via inactivation of the ASK1/JNK signaling pathway.
29 Jul 2026· Journal of molecular histology· PUBMED
Publication
SFPQ/S100A8 complex induces filaggrin deficiency via selective autophagy and JNK phosphorylation in atopic dermatitis.
23 Jul 2026· Cell communication and signaling : CCS· PUBMED

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