New trials, publications, preprints and grants on this target, month by month.
Publication
Brain PDGFRβ+ Cells Exhibit Diverse Reactive Phenotypes After Stroke Without Requiring KLF4.
1 Jan 2027· Glia· PUBMED
Publication
PDGFRβ-Targeting VHH Tracer Enables Noninvasive PET Imaging of Kidney Fibrosis.
5 Nov 2026· Journal of nuclear medicine : official publication, Society of Nuclear Medicine· PUBMED
Publication
Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.
13 Oct 2026· Journal of hematopathology· PUBMED
Publication
Subclonal AGGF1::PDGFRB rearrangement in a myelodysplastic/myeloproliferative neoplasm with suboptimal response to imatinib.
10 Oct 2026· American journal of clinical pathology· PUBMED
Publication
Correction: Anti-PDGFRα autoantibody - a novel diagnostic and prognostic marker - may mediate non-small cell lung cancer progression via the PI3K/AKT/NF-κB signaling pathway.
1 Oct 2026· British journal of cancer· PUBMED
Publication
Novel 1-benzyl-oxindole indole hybrids targeting PDGFR-β, SRC, and c-MET signaling and inducing caspase-3-dependent apoptosis in pancreatic cancer cells.
17 Sept 2026· European journal of medicinal chemistry· PUBMED
Publication
Discovery, Optimization, and Evaluation of Potent and Selective PDGFRβ Inhibitors for the Treatment of Hepatocellular Carcinoma.
10 Sept 2026· Journal of medicinal chemistry· PUBMED
Publication
Biodistribution and radiation dosimetry of the PDGFRβ targeting PET tracer [68Ga]Ga-ATH001.
8 Sept 2026· European journal of nuclear medicine and molecular imaging· PUBMED
Publication
PDGFRA amplification could be a poor prognostic factor of advanced undifferentiated pleomorphic sarcoma in a comprehensive genomic profiling cohort.
7 Sept 2026· Japanese journal of clinical oncology· PUBMED
Publication
KLF2 Is Associated with ERK1/2-MAP2 Activation and Neuron-like Phenotypic Remodeling of PDGFR-β-Lineage Cells Following Ischemic Stroke.
30 Aug 2026· Brain sciences· PUBMED
Publication
ATP6L impairs vascular stability in colorectal cancer via PDGFB/PDGFRβ signaling.
28 Aug 2026· Bioscience trends· PUBMED
Publication
PDGFR-Targeted Ruxolitinib Liposomes Modulate Fibroblast-Associated Colorectal Cancer-Stroma Interactions, Reducing Invasion and Enhancing Chemosensitivity.
25 Aug 2026· ACS omega· PUBMED
Publication
Association of PDGFRB, VEGFR2, and TGFB1 Gene Polymorphisms with Nintedanib Efficacy and Adverse Effects in Patients with Progressive Pulmonary Fibrosis.
23 Aug 2026· International journal of molecular sciences· PUBMED
Publication
miR149-5p: A hepatocyte EXOmotif sequence containing microRNA that attenuates liver fibrosis by specifically targeting PDGFRB in HSCs.
7 Aug 2026· Journal of advanced research· PUBMED
Publication
Acute myeloid leukemia with 4q12 rearrangements involving CHIC2: "pitfalls" in fluorescence in situ hybridization diagnosis of PDGFRA rearrangements.
4 Aug 2026· American journal of clinical pathology· PUBMED
Publication
Imatinib: A Multifunctional Tyrosine Kinase Inhibitor with Diverse Mechanisms Targeting BCR-ABL, c-KIT, and PDGFR in Cancer Therapy.
31 Jul 2026· Current pharmaceutical design· PUBMED
Publication
Case Report: DICER1-mutant primary intracranial sarcoma with concurrent TP53, PDGFRA, and KEAP1 somatic mutations in a 5.5-year-old boy.
30 Jul 2026· Frontiers in oncology· PUBMED
Publication
Blue Rubber Bleb Nevus Syndrome with a Novel PDGFRA Variant and Comorbid Autism Spectrum Disorder: A Case Report.
29 Jul 2026· Children (Basel, Switzerland)· PUBMED
Publication
Golgi-Pattern PDGFRA Immunoreactivity Correlates With PDGFRA Mutation Status in Gastric Epithelioid and Mixed-Type Gastrointestinal Stromal Tumors.
22 Jul 2026· Applied immunohistochemistry & molecular morphology : AIMM· PUBMED
Publication
Epigallocatechin gallate is associated with PDGFRB downregulation and altered PI3K-AKT signaling in gastric cancer.
21 Jul 2026· Translational cancer research· PUBMED
Publication
Retraction Note: Atovaquone inhibits colorectal cancer metastasis by regulating PDGFRβ/NF-κB signaling pathway.
20 Jul 2026· BMC cancer· PUBMED
Publication
PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano-Metabolic Symbiosis: E-Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer.
30 Jun 2026· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publication
A [68Ga]-labeled PDGFRβ-targeting peptide PET probe for assessing MASH-related fibrosis in diet-induced preclinical models and human liver specimens.
30 Jun 2026· Biochemical pharmacology· PUBMED
Publication
Anti-PDGFRα autoantibody - a novel diagnostic and prognostic marker - may mediate non-small cell lung cancer progression via the PI3K/AKT/NF-κB signaling pathway.
27 Jun 2026· British journal of cancer· PUBMED
Publication
Liquid-liquid phase separation-associated gene networks link EMT and ferroptosis to define a PDGFRB-centered prognostic signature in bladder cancer.
24 Jun 2026· Frontiers in immunology· PUBMED
Publication
CCDC88C::PDGFRB-rearranged myeloid neoplasm with predominant neutrophilia and rapid response to imatinib: a molecularly defined case report.
22 Jun 2026· Frontiers in oncology· PUBMED
Publication
First Discovery of the Dual-Functional Inhibitor Targeting VEGFR/PDGFR/CA II for the Treatment of Neovascular Glaucoma.
17 Jun 2026· Journal of medicinal chemistry· PUBMED
Publication
Antitumor and resensitizing effects of wogonin in thyroid cancer via PDGFRB-dependent mechanisms.
22 May 2026· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publication
Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions (FIP1L1::PDGFRA) complicated by Loeffler's endocarditis leading to stroke.
14 May 2026· BMC neurology· PUBMED
Publication
Plasma PDGFRβ and PSD4 methylation levels for non-invasive staging of liver fibrosis.
11 May 2026· Hepatology forum· PUBMED