Target

PRAME

Melanoma antigen preferentially expressed in tumors

4open trials
7trials in total
40publications
0researchers

Diseases

The last 24 months

New trials, publications, preprints and grants on this target, month by month.

TrialsPublicationsPreprintsGrants

Trial
Testing the Anti-Cancer Drug, Brenetafusp (IMCF106C), in Rare Cancers
23 Nov 2026· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publication
PRAME predicting outcome in uveal melanoma.
1 Nov 2026· The journal of pathology. Clinical research· PUBMED
Publication
Association of Age With Gene Expression Profile (GEP) Class and Preferentially Expressed Antigen in Melanoma (PRAME) Expression Status in Uveal Melanoma.
20 Oct 2026· Ophthalmic surgery, lasers & imaging retina· PUBMED
Publication
PRAME Augments K63-Linked Ubiquitination and Stabilization of METTL3 to Promote Lung Adenocarcinoma Metastasis.
19 Oct 2026· MedComm· PUBMED
Publication
PRAME Immunohistochemistry and Molecular Profiling in Undifferentiated Cutaneous Pleomorphic Neoplasms: A Case Series of 8 Tumors.
18 Oct 2026· Journal of cutaneous pathology· PUBMED
Publication
Cytopathology and Prognostic Accuracy of 15-GEP/PRAME: The Collaborative Ocular Oncology Group Study 2.
15 Oct 2026· JAMA ophthalmology· PUBMED
Trial
Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT)
1 Oct 2026· PHASE1 · RECRUITING· CTGOV
Preprint
BAP1 loss and PRAME expression converge to remodel the tumor-immune ecosystem during uveal melanoma progression.
28 Sept 2026· bioRxiv : the preprint server for biology· PUBMED
Publication
Giant dedifferentiated melanoma mimicking soft tissue sarcoma with loss of conventional melanocytic markers: diagnostic utility of PRAME and BRAF V600E immunohistochemistry.
25 Sept 2026· Clinical and experimental dermatology· PUBMED
Publication
PRAME as a Diagnostic Adjunct in Clear Cell Sarcoma.
16 Sept 2026· Applied immunohistochemistry & molecular morphology : AIMM· PUBMED
Publication
Performance of PRAME Immunohistochemistry in Distinguishing Classic Hodgkin Lymphoma from Anaplastic Large Cell Lymphoma and T-Cell Lymphoma.
5 Sept 2026· Cancers· PUBMED
Publication
PRAME promotes invasion and metastasis of salivary adenoid cystic carcinoma by regulating RARα stability via the cullin2 ubiquitin-proteasome system.
1 Sept 2026· Clinical and translational medicine· PUBMED
Publication
PRAME Expression in Merkel Cell Carcinoma: Correlation With MCPyV Status, PD-L1, and Tumor-Infiltrating Lymphocytes in a Multicenter Cohort.
25 Aug 2026· Applied immunohistochemistry & molecular morphology : AIMM· PUBMED
Publication
Quantifying the Interplay Between PRAME Expression and Classical Morphology: A Multivariable Analysis of 954 Suspected Melanocytic Lesions.
3 Aug 2026· Dermatopathology (Basel, Switzerland)· PUBMED
Publication
Demonstration of 23-Gene Expression Profile Test Utility Within PRAME Immunohistochemistry Results: A Case Series.
24 Jul 2026· The American Journal of dermatopathology· PUBMED
Publication
A Novel Nanobody-Based TCR-like CAR T Therapy Targeting PRAME for the Treatment of Acute Myeloid Leukemia.
17 Jul 2026· Clinical cancer research : an official journal of the American Association for Cancer Research· PUBMED
Publication
PRAME immunohistochemistry demonstrates high diagnostic accuracy for distinguishing melanoma from nevi but no observed association with pT stage in cutaneous melanoma: a Vietnamese clinicopathological study.
15 Jul 2026· Diagnostic pathology· PUBMED
Trial
A Phase 1 Study to Evaluate OPB-201 in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.
30 Jun 2026· PHASE1 · RECRUITING· CTGOV
Publication
Characterization of preferentially expressed antigen in melanoma (PRAME) expression in pigmented actinic keratoses and pigmented squamous cell carcinomas in situ.
27 Jun 2026· JAAD international· PUBMED
Publication
PRAME Expression and Melanoma In Situ Margin Assessment.
22 Jun 2026· The American Journal of dermatopathology· PUBMED
Publication
Diagnostic Utility of PRAME Immunohistochemistry for Distinguishing Acral Melanoma From Acral Melanocytic Nevi.
17 Jun 2026· Journal of cutaneous pathology· PUBMED
Publication
The Diagnostic Utility of PRAME in a Case of Trans-Differentiated Melanoma Metastatic to the Heart.
9 Jun 2026· International journal of surgical pathology· PUBMED
Publication
[Diagnostic utility of PRAME immunohistochemistry for distinguishing clear cell sarcoma from malignant melanoma].
8 Jun 2026· Zhonghua bing li xue za zhi = Chinese journal of pathology· PUBMED
Publication
PRAME Expression in HPV-associated and Differentiated Vulvar Intraepithelial Neoplasia-associated Vulvar Squamous Neoplasia.
8 Jun 2026· International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists· PUBMED
Publication
Class 2 PRAME-Positive Ciliochoroidal Melanoma Metastasis to Fellow Eye.
6 Jun 2026· Ophthalmology. Retina· PUBMED
Publication
Circumventing IFN-γ induced resistance in ovarian cancer with a double-hit: NKG2A knockout of PRAME-TCR expressing NK cells.
4 Jun 2026· Journal of ovarian research· PUBMED
Publication
Diagnostic and Prognostic Values of PRAME Immunohistochemistry in Acral Lentiginous Melanoma.
27 May 2026· The American Journal of dermatopathology· PUBMED
Publication
PRAME Immunostaining in Acral Melanocytic Proliferations: A Meta-Analysis.
12 May 2026· The American Journal of dermatopathology· PUBMED
Publication
Prognostic value of PRAME gene promoter methylation and expression in hepatocellular carcinoma.
9 May 2026· Clinical epigenetics· PUBMED
Publication
Clinical utility of 23-gene expression profiling and concordance with PRAME immunohistochemistry in melanocytic neoplasms: A retrospective diagnostic accuracy study.
29 Apr 2026· Journal of the American Academy of Dermatology· PUBMED

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