New trials, publications, preprints and grants on this target, month by month.
Trial
Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers
11 Nov 2026· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publication
A novel SLTM::RUNX1 acquired during CML progression and the clinical significance of concurrent BCR::ABL1 and RUNX1 rearrangements in Ph-positive leukemia.
31 Oct 2026· Cancer genetics· PUBMED
Publication
RUNX1-ETO oncoprotein levels determine the balance between endothelial reprogramming and pre-leukemic growth in a human ES cell model of AML.
19 Oct 2026· Cell reports· PUBMED
Publication
Hematologic Malignancies With RUNX1::ZFPM2 Translocation: A Case Report and Literature Review.
16 Oct 2026· EJHaem· PUBMED
Publication
Acute monocytic leukemia with t(8;22)(p11;q11)/BCR::FGFR1, trisomy 8, and concurrent RUNX1/STAG2 mutations: A rare case report and literature review.
10 Oct 2026· Leukemia research reports· PUBMED
Publication
RUNX1 aberrations in blast-phase chronic myeloid leukaemia induce the RNA-binding protein SPATS2L, which promotes growth, survival and stress granule assembly.
9 Oct 2026· Leukemia· PUBMED
Publication
Sensitivity to ATR-CHK1 pathway inhibition in MDS/AML is enhanced by SRSF2 mutations and reduced by RUNX1 loss.
6 Oct 2026· Leukemia· PUBMED
Publication
RUNX1 links ATF4-associated stress adaptation to microenvironmental remodeling in POSTN+ fibroblasts during skin fibrosis.
18 Sept 2026· Burns & trauma· PUBMED
Publication
Efficacy and Safety of Azacitidine in Patients With RUNX1::RUNX1T1 Measurable Residual Disease-Positive Acute Myeloid Leukemia After Consolidation Therapy Who Did Not Undergo Allogeneic Hematopoietic Stem-Cell Transplantation.
18 Sept 2026· Clinical lymphoma, myeloma & leukemia· PUBMED
Publication
Concurrent RUNX1::MECOM and RUNX1::PRDM16 Fusions from a Novel Genomic Breakpoint: First Report of a Dual-Fusion Mechanism in Acute Myeloid Leukemia.
16 Sept 2026· OncoTargets and therapy· PUBMED
Publication
Genomic Characterization of ETV6::RUNX1-Positive Childhood B-ALL in a Chinese Cohort: Novel Fusion Partners, Co-Occurring Mutations, and Risk-Stratifying Biomarkers.
10 Sept 2026· Pediatric blood & cancer· PUBMED
Publication
Association Between Mutation Context-Associated RUNX1 Transcriptional States and Immune-Stromal Heterogeneity in Nonsmall Cell Lung Cancer.
6 Sept 2026· Human mutation· PUBMED
Publication
AML1-ETO hijacks a distal enhancer of NAT10 to reprogram glutathione metabolism and sustain leukemia stem cell stemness.
1 Sept 2026· Proceedings of the National Academy of Sciences of the United States of America· PUBMED
Publication
The roles of RUNX1 in megakaryocyte differentiation in myeloid leukemia.
24 Aug 2026· Leukemia & lymphoma· PUBMED
Publication
Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high-risk recurrent genetic aberration.
21 Aug 2026· HemaSphere· PUBMED
Publication
Oncogenic DHX15 mutation enhances mitochondrial metabolism and sustains leukemia stemness.
21 Aug 2026· Leukemia· PUBMED
Publication
The Outcomes of Single-unit Unrelated Umbilical Cord Blood Transplantation for Adult Acute Myeloid Leukemia with RUNX1::RUNX1T1 in Multicenter Retrospective analysis.
19 Aug 2026· Transplantation proceedings· PUBMED
Publication
Prognostic Impact of Sequential Measurable Residual Disease and KIT Variant Status in Pediatric Core-Binding Factor Acute Myeloid Leukemia: A Retrospective Multicenter Study of the Taiwan Pediatric Oncology Group.
19 Aug 2026· Annals of laboratory medicine· PUBMED
Publication
Prognostic relevance of RUNX1 mutations at acute myeloid leukemia diagnosis and as measurable residual disease marker before and after allogeneic stem cell transplantation.
13 Aug 2026· Haematologica· PUBMED
Publication
RUNX1 silencing protects against cerebral ischemia/reperfusion injury-induced endoplasmic reticulum stress, inflammation, ferritinophagy and ferroptosis through the CELF2/mTOR axis.
12 Aug 2026· Toxicology and applied pharmacology· PUBMED
Publication
RUNX1-driven endothelial-to-mesenchymal transition contributes to remodelling in LMNA cardiomyopathy.
11 Aug 2026· European heart journal· PUBMED
Publication
RUNX1 upregulation and RUNX1-ETO depletion inhibits survival of t(8;21)-positive leukemia cells.
3 Aug 2026· Global medical genetics· PUBMED
Publication
Psychosocial aspects of RUNX1-familial platelet disorder in adolescents and young adults: "The fear of knowing it could happen sometime down the road".
1 Aug 2026· Journal of genetic counseling· PUBMED
Publication
RUNX1-Driven CPXM1 Transcription Promotes Malignant Phenotypes and EMT in Gastric Cancer Cells.
31 Jul 2026· Cancer science· PUBMED
Publication
CYBRD1 is transcriptionally regulated by RUNX1 and mediates JAK2/STAT3 signaling activation during ovarian cancer progression.
29 Jul 2026· Oncogenesis· PUBMED
Publication
Paris saponin VII promotes TRIP12-mediated SOD1 degradation to synergize with idarubicin in ROS-dependent acute myeloid leukemia cell death.
29 Jul 2026· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publication
EIF4A3-dependent nonsense-mediated decay buffers AML1-ETO9a dosage and modulates outcome in t(8;21) acute myeloid leukemia.
14 Jul 2026· Leukemia· PUBMED
Publication
DHX15 affects AML1-ETO9a splicing together with HNRNPL, RBM33 in AML1-ETO-positive acute myeloid leukaemia.
12 Jul 2026· British journal of haematology· PUBMED
Publication
Targeting RUNX1 protects against diastolic dysfunction in a two-hit mouse model of heart failure with preserved ejection fraction.
11 Jul 2026· Cardiovascular research· PUBMED
Publication
A special multifiber dietary mixture ameliorates Crohn's-like colitis in an IL-10-/- mouse model by promoting treg differentiation through the ETS1/RUNX1/Foxp3 axis.
3 Jul 2026· European journal of nutrition· PUBMED