New trials, publications, preprints and grants on this target, month by month.
Trial
Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis
11 Nov 2026· PHASE1 · RECRUITING· CTGOV
Publication
Retraction Note: Circular RNA hsa_circ_0068871 regulates FGFR3 expression and activates STAT3 by targeting miR-181a-5p to promote bladder cancer progression.
5 Nov 2026· Journal of experimental & clinical cancer research : CR· PUBMED
Publication
Dihydrotanshinone I in Paired Vemurafenib-Sensitive and Resistant A375 Melanoma Cells.
5 Nov 2026· Journal of visualized experiments : JoVE· PUBMED
Publication
Statement of Retraction: MACC1 regulates the AKT/STAT3 signaling pathway to induce migration, invasion, cancer stemness, and suppress apoptosis in cervical cancer cells.
5 Nov 2026· Bioengineered· PUBMED
Publication
Impact of nano-chitosan solution on psoriasis-like thin skin lesion induced by imiquimod in Wistar rats: Exploring novel epigenetic role targeting miR-155, JAK2/STAT3/RORC/IL-17A, and MyD88/NF-κB pathways.
4 Nov 2026· Histology and histopathology· PUBMED
Publication
NOP2/Sun domain 4-mediated m5C methylation of Janus kinase 1 promotes hepatocellular carcinoma progression.
4 Nov 2026· Cell adhesion & migration· PUBMED
Publication
INHBA Inhibits ANXA9 Ubiquitination and Activates STAT3 to Drive Gastric Cancer Proliferation and Metastasis.
4 Nov 2026· Archives of biochemistry and biophysics· PUBMED
Publication
Danvatirsen plus Pembrolizumab versus Pembrolizumab for Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma (PEMDA-HN): A Randomized, Phase II Trial.
2 Nov 2026· Clinical cancer research : an official journal of the American Association for Cancer Research· PUBMED
Trial
A Study of MDSY-1240, a STAT3 Degrader, for the Treatment of Hematologic Malignancies and Advanced Solid Tumors
1 Nov 2026· PHASE1_PHASE2 · NOT_YET_RECRUITING· CTGOV
Publication
The Histone Lactylation of KREMEN2 Inhibits Ferroptosis Through the JAK2/STAT3/GPX4 Axis and Promotes the Progression of Mantle Cell Lymphoma.
1 Nov 2026· Hematological oncology· PUBMED
Publication
Ferroportin deficiency drives olaparib resistance in ovarian cancer via the cGAS-STING-STAT3 survival axis.
1 Nov 2026· Clinical and translational medicine· PUBMED
Publication
Bone marrow mesenchymal stem cells relieve rheumatoid arthritis by blocking JAK/STAT and TLR-4/NF-κB pathways.
1 Nov 2026· Pakistan journal of pharmaceutical sciences· PUBMED
Publication
Serpin A1 Cargo Within Tumour-Derived Extracellular Vesicles Supports Pro-Tumoural Bias of Neutrophils in Cancer.
1 Nov 2026· Journal of extracellular vesicles· PUBMED
Publication
Jolkinolide B induces apoptosis and G1 arrest in A549 cells via JAK2/STAT3 inhibition.
1 Nov 2026· Pakistan journal of pharmaceutical sciences· PUBMED
Publication
MAGI3 Acts as an Intestinal Epithelial Gatekeeper in Inflammation-Associated Colorectal Cancer by Suppressing the STAT3-CCL2 Axis and TAM-Mediated Immunosuppression.
31 Oct 2026· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publication
Acquired TRAIL Resistance Promotes Cancer Stemness and Malignant Behavior through CD44-SPHK1-STAT3 Signaling in Colorectal Cancer.
30 Oct 2026· Biomolecules & therapeutics· PUBMED
Publication
LMP2A Promotes Immune Escape by Regulating PD-L1 Expression via the PI3K/AKT/STAT3 Axis in EBV-Positive Gastric Cancer.
30 Oct 2026· Experimental cell research· PUBMED
Publication
Recombinant RANKL protects against brain injury in intracerebral haemorrhage by regulating microglial phenotypes via the STAT3 pathway.
29 Oct 2026· Brain injury· PUBMED
Publication
A pectic polysaccharide from Lonicera japonica alleviates DNCB-induced atopic dermatitis-like inflammation associated with gut microbial and metabolic alterations and reduced cutaneous JAK2/STAT3 activation and Th17 responses.
29 Oct 2026· Journal of ethnopharmacology· PUBMED
Publication
CXCL9 Knockdown Inhibits Tumor Progression and Angiogenesis in Clear Cell Renal Cell Carcinoma via JAK-STAT3 Signaling Pathway.
28 Oct 2026· Oncology research· PUBMED
Publication
Collagen type I alpha 1 chain induces M2 macrophage polarization via integrin α2β1/JAK2/STAT3 pathway to promote gastric cancer progression.
28 Oct 2026· Tissue & cell· PUBMED
Publication
RNA binding motif protein 15 (RBM15) inhibits macrophage phagocytosis via m6A-dependent colony stimulating factor 2 (CSF2)/STAT3 pathway in pancreatic cancer.
28 Oct 2026· International journal of biological macromolecules· PUBMED
Publication
An MMP-14/STAT3 feedback loop upregulates PD-L1 to drive immunosuppression and tumorigenesis in bladder cancer.
28 Oct 2026· iScience· PUBMED
Publication
Disruption of the N-terminal domain in a STAT3 hyper-IgE syndrome variant causes disease by sequestering STAT3 in the cytoplasm.
27 Oct 2026· Science signaling· PUBMED
Publication
Low expression of SGPL1 promotes HCC progression by modulating LacCer metabolism via the S1P-STAT3-B4GALT6 axis.
26 Oct 2026· Journal of lipid research· PUBMED
Publication
Retraction: Resveratrol eliminates cancer stem cells of osteosarcoma by STAT3 pathway inhibition.
26 Oct 2026· PloS one· PUBMED
Publication
Calsyntenin-2 promotes the pathology of acute myeloid leukemia via activation of the JAK2-STAT3 signaling pathway.
25 Oct 2026· Cellular signalling· PUBMED
Publication
[Research progress on the multi-target modulation of signaling pathways by acupuncture in the treatment of obesity].
25 Oct 2026· Zhen ci yan jiu = Acupuncture research· PUBMED
Publication
Repurposing the bitter taste receptor TAS2R14 as a pro-ferroptotic driver in thyroid cancer via the STAT3-HCG11-miR-450b-5p axis.
25 Oct 2026· Acta biochimica et biophysica Sinica· PUBMED
Publication
Artesunate targets STAT3 to alleviate Hodgkin's lymphoma via JAK-STAT/PD-L1 axis.
24 Oct 2026· Biochemical pharmacology· PUBMED