New trials, publications, preprints and grants on this target, month by month.
Publication
ENPP1 inhibits the cGAS-STING pathway to mediate immune evasion in EGFR-TKI-resistant non-small cell lung cancer.
5 Nov 2026· Cell death and differentiation· PUBMED
Publication
Engineered T cell-agonist chimera for logic-gated STING activation and augmented cancer immunotherapy.
3 Nov 2026· Proceedings of the National Academy of Sciences of the United States of America· PUBMED
Publication
Simiao Pill ameliorates collagen-induced arthritis in association with gut-joint axis modulation and attenuation of cGAS-STING signaling.
3 Nov 2026· Journal of ethnopharmacology· PUBMED
Publication
STING-dependent TNF signalling promotes IKKβ-mediated ATG9A phosphorylation and autophagy.
3 Nov 2026· Nature cell biology· PUBMED
Publication
Ferroportin deficiency drives olaparib resistance in ovarian cancer via the cGAS-STING-STAT3 survival axis.
1 Nov 2026· Clinical and translational medicine· PUBMED
Publication
Repurposing the orphan drug nitisinone synergizes with sorafenib to sensitize immunotherapy-refractory MSS-CRC via metabolic stress-driven STING activation.
30 Oct 2026· Pharmacological research· PUBMED
Publication
Cascade-Catalytic MnO2 Nanoreactor Amplifies Oxidative Stress and Activates cGAS-STING Pathway To Remodel the Immunosuppressive Microenvironment of Triple-Negative Breast Cancer.
28 Oct 2026· ACS applied materials & interfaces· PUBMED
Publication
Therapeutic effect of quercetin on airway remodeling of ovalbumin-induced asthmatic mice via inhibition of the mtDNA-cGAS-STING pathway.
27 Oct 2026· Molecular and cellular biochemistry· PUBMED
Publication
The Tango of cGAS-STING and Phagocytosis in Disease: From Molecular Mechanisms to Pharmacological Targeting.
24 Oct 2026· Drug design, development and therapy· PUBMED
Publication
Targeting histone methylation with ROS nanoparticles delivering PARPi prodrugs to amplify the stimulation of cGAS-STING for immunotherapy in ovarian cancer.
23 Oct 2026· Materials today. Bio· PUBMED
Publication
Targeting STING to attenuate autophagy-mediated airway remodeling in asthma.
23 Oct 2026· Molecular and cellular biochemistry· PUBMED
Publication
Engineered mitochondria-derived vesicles suppress colorectal cancer through metabolic reprogramming and mtDNA-cGAS-STING signaling.
22 Oct 2026· Cellular signalling· PUBMED
Publication
CREBBP loss drives immune evasion by epigenetically silencing STING and MHC-I in small cell lung cancer.
21 Oct 2026· Science advances· PUBMED
Publication
Anti-PD-L1 antibody-coated metal-organic framework for targeted PTPN2 Inhibitor delivery and enhanced immunotherapy of head and neck squamous cell carcinoma via cGAS-STING activation.
20 Oct 2026· International journal of pharmaceutics: X· PUBMED
Publication
[40 Hz flicker light stimulation suppresses STING signaling to improve cognitive dysfunction in mice with Parkinson disease].
20 Oct 2026· Nan fang yi ke da xue xue bao = Journal of Southern Medical University· PUBMED
Publication
Context-dependent cGAS-STING signaling in inflammatory bowel disease: cell specificity, lesion state, and therapeutic windows.
20 Oct 2026· Frontiers in immunology· PUBMED
Publication
Context-dependent cGAS-STING signaling in solid tumors: biological determinants, clinical implications, and biomarker-guided therapeutic strategies.
19 Oct 2026· Frontiers in immunology· PUBMED
Publication
Immunotoxicological mechanism of a dual-targeted nanocomposite: Mitochondrial stress-driven cGAS-STING activation in lung cancer.
16 Oct 2026· Colloids and surfaces. B, Biointerfaces· PUBMED
Publication
Developing a Better Hepatocellular Carcinoma Treatment: AlEu MOF Nanoparticles Enhance Microwave Thermal Ablation and Synergistically Activate the cGAS-STING Pathway.
16 Oct 2026· International journal of nanomedicine· PUBMED
Publication
Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging.
15 Oct 2026· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publication
Single-Cell Analysis of Residual Esophageal Squamous Cell Carcinoma after Neoadjuvant Immunochemotherapy Reveals TFAM-Mediated Immunoregulation in Dendritic Cells.
15 Oct 2026· Cancer research· PUBMED
Publication
Metabolic Competition-Driven Antitumor Immunity of glpX-Deficient Engineered Salmonella via Glucose Deprivation and STING Activation in Bladder Cancer.
15 Oct 2026· Cancer communications (London, England)· PUBMED
Publication
NAD+ Attenuates Neuroinflammation in Ischemic Stroke by Suppressing the cGAS- STING Pathway via Mitochondrial Homeostasis Restoration.
14 Oct 2026· Molecular neurobiology· PUBMED
Publication
CCNE1 overexpression drives a cGAS-STING-dependent interferon response and sensitizes HRD-positive ovarian cancer to immune checkpoint blockade.
14 Oct 2026· Journal for immunotherapy of cancer· PUBMED
Publication
Targeting Macrophage STING O-GlcNAcylation via Small-Molecule Allosteric Modulation for Psoriasis Therapy.
14 Oct 2026· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publication
Polygonatum sibiricum polysaccharide attenuates BMSC senescence by inhibiting NCOA4-mediated ferritinophagy.
14 Oct 2026· Pharmaceutical biology· PUBMED
Publication
The cGAS-STING pathway in metabolic dysfunction-associated steatotic liver disease: mechanistic insights and therapeutic opportunities.
13 Oct 2026· Frontiers in pharmacology· PUBMED
Publication
The cGAS-STING signaling axis in Type 2 diabetes-associated cognitive decline: from mitochondrial DNA sensing to neurodegeneration.
12 Oct 2026· Acta diabetologica· PUBMED
Publication
CISD1 suppresses COPD inflammation by recruiting ubiquitinated STING and altering macrophage metabolism.
12 Oct 2026· Respiratory research· PUBMED
Publication
Stimulator of Interferon Genes (STING) Agonist-Loaded Copper-Based Nanoparticles for B7-H3 Blockade-Enhanced Chemodynamic-Immunotherapy of Ovarian Cancer.
10 Oct 2026· International journal of nanomedicine· PUBMED