New trials, publications, preprints and grants on this target, month by month.
Trial
Expression of TSLP Isoforms in Asthma
26 Aug 2026· NA · RECRUITING· CTGOV
Publication
TSLP impairs mucociliary transport by inhibiting JAK signaling in both central and peripheral airways.
4 Aug 2026· Pflugers Archiv : European journal of physiology· PUBMED
Publication
Tezepelumab Reverses TSLP-Driven Immunometabolic Rewiring in Human cDC2s Underlying Pathogenic Th2 and Dysfunctional Treg Responses.
31 Jul 2026· Allergy· PUBMED
Publication
Chebulinic acid suppresses NF-κB/TSLP signaling axis via ACLY-mediated lipid metabolism reprogramming to ameliorate atopic dermatitis.
16 Jul 2026· Journal of ethnopharmacology· PUBMED
Trial
Efficacy of an Anti-TSLP Monoclonal Antibody in the Management of Chronic Bronchial Disease Induced by Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Stem Cells Transplantation Recipients
24 Jun 2026· PHASE2 · RECRUITING· CTGOV
Trial
A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)
2 Jun 2026· PHASE2 · RECRUITING· CTGOV
Publication
First-in-human, phase 1 study of CM512, a TSLP/IL-13 bispecific antibody, in healthy volunteers: safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity.
28 May 2026· Frontiers in immunology· PUBMED
Publication
Epithelial alarmins TSLP, IL-33, and IL-25 in asthma pathogenesis: mechanistic roles and therapeutic implications.
26 May 2026· Molecular biology reports· PUBMED
Publication
Tezepelumab: redefining TSLP blockade in severe asthma through mechanistic precision and translational pharmacology.
24 Apr 2026· Frontiers in pharmacology· PUBMED
Publication
CM512, a potentially novel IgG1-based bispecific antibody dual-targeting TSLP and IL-13, for the suppression of type 2 inflammation.
10 Apr 2026· Journal of translational medicine· PUBMED
Publication
Kaempferol-7-O-Glucoside Ameliorates Atopic Dermatitis via the TSLP-Mediated JAK2/STAT5 Signaling Axis.
4 Apr 2026· Pharmaceuticals (Basel, Switzerland)· PUBMED
Publication
Safety, Tolerability, and Pharmacokinetics of HBM9378 (SKB378/WIN378), a Fully Human IgG1 Monoclonal Antibody Against TSLP After Single Ascending Doses in Chinese Healthy Subjects.
18 Mar 2026· Drug design, development and therapy· PUBMED
Publication
Thymic stromal lymphopoietin (TSLP) - pro-inflammatory cytokine and antimicrobial peptide.
4 Mar 2026· Biochimica et biophysica acta. Molecular cell research· PUBMED
Publication
QX008N, an Anti-TSLP Monoclonal Antibody: Pharmacokinetics, Tolerability, and Immunogenicity in Healthy Chinese Subjects.
1 Mar 2026· Clinical and translational science· PUBMED
Trial
A Phase 2 Trial of JKN24011 in COPD
27 Feb 2026· PHASE2 · COMPLETED· CTGOV
Publication
Beyond inhaled medications: precision medicine and biologic therapies targeting the IL-33/TSLP/type 2 axis in COPD.
5 Feb 2026· Frontiers in immunology· PUBMED
Publication
Oxidative stress induced TSLP production via TRPV4 regulates type 2 inflammation and pruritus in MC903 induced atopic dermatitis mouse model.
31 Jan 2026· Journal of dermatological science· PUBMED
Publication
Direct targeting of STAT3 by xanthatin suppresses allergic airway inflammation via inhibition of TSLP release and NK2 cell polarization.
30 Jan 2026· Journal of ethnopharmacology· PUBMED
Publication
The predictive value of combined detection of serum IL-33, TSLP and eosinophils in the treatment effect and exacerbation risk of chronic obstructive pulmonary disease.
28 Jan 2026· BMC pulmonary medicine· PUBMED
Publication
TSLP promotes GATA3-expressing effector regulatory T cells via DC2 derived from transitional DCs.
27 Jan 2026· Nature immunology· PUBMED
Publication
Dupilumab attenuates the expression of TSLP and IL-8 induced by dsRNA and IL-4/IL-13 co-stimulation in human small airway epithelial cells.
23 Jan 2026· PloS one· PUBMED
Publication
Magnolia officinalis Rehder & E. Wilson extract and its main component honokiol alleviate asthma by reducing respiratory inflammation through the TRPV1/NFAT/TSLP pathway.
16 Jan 2026· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publication
Retraction: Effects of microRNA-19b on airway remodeling, airway inflammation and degree of oxidative stress by targeting TSLP through the Stat3 signaling pathway in a mouse model of asthma.
6 Jan 2026· Oncotarget· PUBMED
Publication
Enhanced Alarmin Secretion Exacerbates Neutrophil Extracellular Trap (NET) Formation in Active Psoriasis: Implication of IL-33 and TSLP in Driving NET Formation, Inflammation and Oxidative Stress in Psoriasis.
6 Jan 2026· Antioxidants (Basel, Switzerland)· PUBMED
Publication
Role of Cytokines IL-25, IL-33, and TSLP in the Respiratory Tract Inflammation: Therapeutic Perspectives.
1 Jan 2026· Biochemistry. Biokhimiia· PUBMED
Publication
[THE ROLE OF TSLP IN THE PATHOGENESIS OF ALLERGIC DISEASES AND FUTURE THERAPEUTIC PERSPECTIVES].
1 Jan 2026· Arerugi = [Allergy]· PUBMED
Publication
Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32-Week Randomized Phase 1b Multiple Ascending-Dose Trial.
24 Dec 2025· Clinical pharmacology and therapeutics· PUBMED
Publication
Release of Airway Alarmins IL-33 and TSLP in Paediatric Acute Severe Asthma: A Case-Control Study.
12 Dec 2025· Acta paediatrica (Oslo, Norway : 1992)· PUBMED
Publication
A Bispecific Antibody Blocking Both TSLP and IL-4Rα for the Treatment of Allergic Inflammatory Diseases.
7 Nov 2025· Cells· PUBMED
Trial
Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma
24 Jul 2025· PHASE2 · RECRUITING· CTGOV