2022-502164-20-01RecruitingPhase 4
Semaglutide 2.4mg for low responders after bariatric surgery
Source: EU CTIS (euclinicaltrials.eu) · Last updated 6 Mar 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
To study the weight change from 3 to 18 months after surgery (% total weight loss, TWL) in low responders after bariatric surgery who are treated with Semaglutide 2.4 mg and a lifestyle intervention and compare change in weight to patients receiving placebo and a lifestyle intervention.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 152 (estimated)
- First submitted
- 15 Nov 2023
- Start date
- 11 Mar 2025
- Lead sponsor
- Stichting Zuyderland Medisch Centrum
- Diseases
- Obesity
- EU CT number
- 2022-502164-20-01
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 152
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Other illness
- Type 1 or type 2 diabetes
- Liver failure (all)
- Congestive heart failure or angina pectoris NYHA class III and IV
- Malignancy in history
- Inflammatory Bowel Disease
- Thyroid malignancy in history
Lab values
- Decreased renal function (creatinine clearance < 30 ml/min)
Other
- Use of warfarin or other coumarin derivates
- Pancreatitis (in history)
- Pregnancy / breast-feeding
Who the study is looking for
- Patient is ≥18 and <75 years old
- BMI before surgery was ≥ 35.0 kg/m2
- Patient is treated with group consultation at the Dutch Obesity Clinic (DOC)
- Patient has undergone a primary (banded) RYGB or (banded) sleeve gastrectomy (SG)
- Patient is in the lowest %TWL quartile, 3 months after surgery and will be enrolled in the plus module.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rode Kruis Ziekenhuis B.V. | Beverwijk | Netherlands | Recruiting |
| Zuyderland Medisch Centrum Stichting | Heerlen | Netherlands | Recruiting |
| Sint Antonius Ziekenhuis Stichting | Nieuwegein | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.