2022-503135-33-00RecruitingPhase 4
TREASURE trial
Timely recovery after subclinical heart failure
Source: EU CTIS (euclinicaltrials.eu) · Last updated 28 Jul 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The main-objective is to evaluate the effect of an angiotensin-converting-enzyme (ACE) inhibitor compared to care as usual (i.e. no medication) during a two-year open-labeled treatment period in women with asymptomatic heart failure (HF) on reversibility of aberrant cardiac remodeling in asymptomatic HF towards healthy values.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 130 (estimated)
- First submitted
- 29 Apr 2023
- Start date
- 26 Mar 2024
- Lead sponsor
- University Hospital Maastricht
- Diseases
- Heart failure
- EU CT number
- 2022-503135-33-00
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 130
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Already using antihypertensive medication
- Women have the intention to pursue pregnancy within 2 years (as ACE inhibitors may be teratogenic)
- Auto-immune disease(s) prior to the (complicated) pregnancy
- Chronic hypertension prior to the complicated pregnancy
Lab values
- Suffering diabetes mellitus, kidney failure (GFR<60 ml/min/1.73m2), pre-existent auto-immune disease and/or liver insufficiency
Other
- Systolic blood pressure of ≥180 mmHg and/or diastolic blood pressure of ≥110 mmHg
- Breastfeeding during participation
- Women who do not want themselves and/or their general practitioner and specialist(s) to be informed about the test results
Who the study is looking for
- Women, aged 18 years and older
- Heart failure stage-B or diastolic dysfunction
- Premenopausal, with or without a history of preeclamptic pregnancy
- ≥½ and ≤ 30 years after the (first) (complicated) pregnancy;
- Last delivery at least 6 months ago
Age in the registry: 18 years to 64 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Maastricht | Maastricht | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.