2023-504171-24-00Active, not recruitingPhase 4
DUPI REDUCE trial (DUPIlumab dose REDUCtion in patients with controlled atopic Eczema): a multicenter, low-intervention, non-inferiority randomized controlled trial, embedded in the TREAT NL registry.
Source: EU CTIS (euclinicaltrials.eu) · Last updated 2 Dec 2024
Brief summary (registry, in English)
To evaluate and compare the efficacy of dupilumab 300 mg every 2 weeks, every 3 weeks and every 4 weeks, 16 weeks after randomization.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 216 (estimated)
- First submitted
- 23 Mar 2023
- Start date
- 14 Aug 2023
- Lead sponsor
- Amsterdam UMC
- Diseases
- Atopic dermatitis (eczema)
- EU CT number
- 2023-504171-24-00
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 216
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- The subject uses or initiates other systemic immunomodulating therapy for atopic eczema or another diagnosis.
Who the study is looking for
- The subject is an adult.
- The subject has a diagnosis of atopic eczema.
- The subject receives dupilumab 300 mg every 2 weeks for the treatment of atopic eczema.
- The subject has controlled disease according to the Treat-to-Target criteria.
- The subject has voluntarily signed and dated an informed consent prior to any study related procedure or has a legal representative to do so and is willing to comply with the requirements of this study protocol.
Age in the registry: 18 years to 64 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Flevoziekenhuis Stichting | Almere | Netherlands | Active, not recruiting |
| Amsterdam UMC | Amsterdam | Netherlands | Active, not recruiting |
| Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC) | Rotterdam | Netherlands | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.