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2023-504696-24-00Not yet recruitingPhase 1/2

The ALPINE trial: a phase 1-2 study of intra-arterial [177Lu]Lu-PSMA-I&T for progressive or recurrent intracranial adult type diffuse glioma

Source: EU CTIS (euclinicaltrials.eu) · Last updated 13 May 2026

Next steps

Status (registry)
Not yet recruiting
Phase (registry)
Phase 1/2
Study type
Interventional
Enrollment
28 (estimated)
First submitted
20 Apr 2023
Start date
1 Dec 2025
Lead sponsor
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Diseases
Glioblastoma
EU CT number
2023-504696-24-00

What you commit to

  • Study type: Interventional · Phase 1/2
  • Planned participants: 28
  • 2 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.

AI-kivonat: who the study is looking for

Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with a brain tumour called diffuse glioma that has grown or come back.

Age
18 to 64 years
Sex
All sexes can join.
Disease stage
Diffuse glioma (diffuse astrocytoma, oligodendroglioma or glioblastoma) inside the skull that is progressing or has recurred.

Read by machine on 9 Nov 2026.

Sites (2)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)RotterdamNetherlandsNot yet recruiting
St. Olavs hospital HFTrondheimNorwayNot yet recruiting

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This page is information, not medical advice. Discuss any trial with your doctor.