2023-504826-21-00CompletedPhase 2
Phase 2a, double-blind, randomized, placebo-controlled trial of methylprednisolone versus placebo in patients with cognitive deficits in post-COVID-19 syndrome (PCS) - PoCoVIT
Source: EU CTIS (euclinicaltrials.eu) · Last updated 13 Nov 2024
Brief summary (registry, in English)
Improvement in memory satisfaction from baseline to week 8 when comparing methyl-prednisolone with placebo in PCS patients
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 418 (actual)
- First submitted
- 31 Mar 2023
- Start date
- 2 Jul 2024
- Lead sponsor
- Charite Universitaetsmedizin Berlin KöR
- Diseases
- Long COVID and ME/CFS
- EU CT number
- 2023-504826-21-00
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 418
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous medical history of gastric ulcer, osteoporosis and/or previous vertebral fractures, rheumatological disease or metabolic disease including diabetes mellitus
- Ongoing immunosuppressive therapy
Other illness
- Any ongoing central nervous system disease
- Any major psychiatric disease within the last 10 years
Other
- Patient is pregnant or breastfeeding at screening
Who the study is looking for
- History of confirmed (PCR or serology or rapid antigen detection and sick note or comparable certificate after Dec 21, 2023) SARS-CoV-2 infection according to WHO criteria
- Ongoing symptoms of PCS for ≥ 3 months
- Self-reported cognitive deficits at screening
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Charite Universitaetsmedizin Berlin KöR | Berlin | Germany | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.