2023-505122-34-00Active, not recruitingPhase 3
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants with Plaque Psoriasis Involving Special Areas
Source: EU CTIS (euclinicaltrials.eu) · Last updated 28 Aug 2026
Brief summary (registry, in English)
To evaluate the efficacy of JNJ-77242113 in participants with plaque psoriasis with at least moderate severity affecting special areas or lower BSA (range: ≥5% to <10%) moderate to severe plaque psoriasis.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 161 (estimated)
- First submitted
- 7 Aug 2023
- Start date
- 5 Dec 2023
- Lead sponsor
- Janssen - Cilag International
- Diseases
- Psoriasis
- EU CT number
- 2023-505122-34-00
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 161
- 36 sites in 4 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current drug-induced psoriasis.
Other illness
- A current diagnosis or signs or symptoms of severe, progressive, or uncontrolled renal, liver, cardiac, vascular, pulmonary, gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, psychiatric, or metabolic disturbances.
- Known allergies, hypersensitivity, or intolerance to JNJ-77242113 or its excipients.
Other
- Nonplaque form of psoriasis.
- Dermatoses other than plaque psoriasis or palmoplantar pustulosis of the palmoplantar area.
Who the study is looking for
- ≥12 years of age at the screening visit.
- Diagnosis of plaque psoriasis, with or without PsA, for at least 26 weeks prior to the first administration of study intervention.
- Candidate for phototherapy or systemic treatment for plaque psoriasis.
- Need to meet criteria (a) and/or (b) a. Total BSA ≥1% at screening and baseline, AND IGA (overall) ≥2 at screening and baseline AND at least one of the following: - ss-IGA score ≥3 at screening and baseline, and/or - sPGA-G ≥3 at screening and baseline, and/or - hf-PGA score ≥3 at screening and baseline.
- Failed to respond to at least 1 topical therapy used for treatment of psoriasis.
Sex: All · Does not accept healthy volunteers
Sites (36)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ISA - Interdisciplinary Study Association GmbH | Berlin | Germany | Active, not recruiting |
| CRS Clinical Research Services Management GmbH | Berlin | Germany | Active, not recruiting |
| Dr. Niesmann And Dr. Othlinghaus GbR | Bochum | Germany | Active, not recruiting |
| Rosenpark Research Gmbh | Darmstadt | Germany | Active, not recruiting |
| Technische Universität Dresden | Dresden | Germany | Active, not recruiting |
| Goethe University Frankfurt | Frankfurt Am Main | Germany | Active, not recruiting |
| Dermatologikum Hamburg Gmbh | Hamburg | Germany | Active, not recruiting |
| Hautarztpraxis Dr. Hoffmann | Witten | Germany | Active, not recruiting |
| Hospital Germans Trias i Pujol | Badalona | Spain | Active, not recruiting |
| Hospital del Mar | Barcelona | Spain | Active, not recruiting |
| Sant Joan De Deu Barcelona Hospital | Esplugues De Llobregat | Spain | Active, not recruiting |
| Hospital Universitario Clínico San Cecilio | Granada | Spain | Active, not recruiting |
| Hospital Universitario 12 de Octubre | Madrid | Spain | Active, not recruiting |
| Hospital de Manises | Manises | Spain | Active, not recruiting |
| Hospital Universitario Virgen De La Macarena | Sevilla | Spain | Active, not recruiting |
| Hospital Universitario Y Politecnico La Fe | Valencia | Spain | Active, not recruiting |
| Obudai Egeszsegugyi Centrum Kft. | Budapest III | Hungary | Active, not recruiting |
| Derma-B Kft. | Debrecen | Hungary | Active, not recruiting |
| University of Debrecen | Debrecen | Hungary | Active, not recruiting |
| Somogy Vármegyei Kaposi Mór Oktató Kórház | Kaposvár | Hungary | Active, not recruiting |
| University of Pecs | Pécs | Hungary | Active, not recruiting |
| University of Szeged | Szeged | Hungary | Active, not recruiting |
| Allergo-Derm Bakos Kft | Szolnok | Hungary | Active, not recruiting |
| Medmare Bt. | Veszprém | Hungary | Active, not recruiting |
| Osteo Medic s.c. Artur Racewicz Jerzy Supronik | Bialystok | Poland | Active, not recruiting |
| Specderm Poznanska sp.j. | Bialystok | Poland | Active, not recruiting |
| Centrum Medyczne Dr Rajzer Sp. z o.o. | Cracow | Poland | Active, not recruiting |
| Promed P.Lach R.Glowacki Sp. j. | Cracow | Poland | Active, not recruiting |
| Specjalistyczny Gabinet Dermatologiczny Aplikacyjno Badawczy Marek Brzewski Paweł Brzewski s.c. | Krakow | Poland | Active, not recruiting |
| DERMED Centrum Medyczne Sp. z o.o. | Lodz | Poland | Active, not recruiting |
| Solumed Centrum Medyczne Sp. z o.o. | Poznan | Poland | Active, not recruiting |
| Clinical Research Center Sp z o o Medic R Sp k | Poznan | Poland | Active, not recruiting |
| Klinika Ambroziak Sp. z o.o. | Warsaw | Poland | Active, not recruiting |
| Dorota Bystrzanowska High-Med. Przychodnia Specjalistyczna | Warsaw | Poland | Active, not recruiting |
| Centrum Medyczne Oporow | Wroclaw | Poland | Active, not recruiting |
| WroMedica I Bielicka A Strzalkowska s c | Wroclaw | Poland | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.