2023-505453-40-00Not yet recruitingPhase 1/2
DUAL
99mTechnetium and Cyanine-5 (HybriD) Prostate Specific Membrane Antigen (PSMA) Tracer-gUided Surgery in ProstAte Cancer - a FeasibiLity Study (DUAL study)
Source: EU CTIS (euclinicaltrials.eu) · Last updated 11 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
To confirm lesion-specific uptake of 99mTc-hPSMA by PCa
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 13 (estimated)
- First submitted
- 25 Apr 2025
- Start date
- 1 Aug 2025
- Lead sponsor
- Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
- Diseases
- Prostate cancer
- EU CT number
- 2023-505453-40-00
What you commit to
- Study type: Interventional · Phase 1/2
- Planned participants: 13
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous radiotherapy of the abdomen
- Ongoing androgen deprivation therapy (ADT) or within 6 months prior to surgery
- Previous or ongoing chemotherapy
- Previous or ongoing immunotherapy
Other illness
- History of other malignancy within 5 years prior to surgery (except skin malignancies)
- History of clinically significant allergies including anaphylaxis
Lab values
- History of impaired renal function (defined as eGFR<60ml/min/1,73m2)
Other
- Severe claustrophobia interfering with PET/CT or SPECT/CT scanning
Who the study is looking for
- Male, aged 18 years and older
- Histopathologically confirmed adenocarcinoma of the prostate
- Had a routine PSMA PET/CT within 90 days before surgery
- PSMA avid tumor on PSMA PET/CT
- Suitable for RALP +ePLND, as per institutional guidelines (no minimum or maximum lesions on PSMA PET)
- Written and signed informed consent
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting | Amsterdam | Netherlands | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.