2023-506949-27-00CompletedPhase 2
Identifying Individuals at Risk of Glucocorticoid-Induced Impairment of Bone Disease (RIGID
Identifying Individuals at Risk of Glucocorticoid-Induced Impairment of Bone Disease (RIGID)
Source: EU CTIS (euclinicaltrials.eu) · Last updated 5 Dec 2025
Brief summary (registry, in English)
The main objective of the study is to detect a biomarker(s) that identifies individuals at risk of Glucocorticoid-Induced Impairment of Bone Disease
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 22 Jan 2024
- Start date
- 14 Oct 2024
- Lead sponsor
- Odense University Hospital
- Diseases
- Osteoporosis
- EU CT number
- 2023-506949-27-00
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 36
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Vaccination with living or weaken viral or bacterial vaccines in patient who or immunocompromised. In these cases, prednisolone treatment should not be administered two weeks before and after vaccination.
- Previous gastric bypass and/or known ongoing malabsorption
Other illness
- Allergy to prednisolone or one of the excipients
- Systematic fungal infections
- Not able to provide informed consent (e.g., dementia, not able to understand Danish). At the information meeting the investigator will make an individual assessment to evaluate whether a potential study participants understand the information.
- Known Cushing’s syndrome
- Severe covid-19 in the last 3 month (defined as needing dexamethasone treatment)
- Menopause (defined as 1 year without menstrual bleeding)
- Ongoing infection
Lab values
- Chronic kidney disease (eGFR <30)
Other
- Uncontrolled thyrotoxicosis
- Use of oral or inhaled GCs within the past year
- Pregnancy (defined as elevated HCG)
Who the study is looking for
- Men and women aged 18-50 years
Age in the registry: 18 years to 64 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Esbjerg Og Grindsted Sygehus | Esbjerg | Denmark | Completed |
| Odense University Hospital | Odense C | Denmark | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.