2023-507655-30-00Active, not recruitingPhase 3
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
I8F-MC-GPIX: Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo for the Treatment of Obesity and Weight-Related Comorbidities in Adolescents: A Randomized, Double-Blind, Placebo- Controlled Trial (SURMOUNT-ADOLESCENTS-2)
Source: EU CTIS (euclinicaltrials.eu) · Last updated 18 Aug 2026
Brief summary (registry, in English)
1. To demonstrate that tirzepatide MTD is superior to placebo for achieving BMI reduction. 2. To demonstrate that tirzepatide MTD is superior to placebo for improvement in weight-related comorbidities.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 43 (estimated)
- First submitted
- 27 May 2024
- Start date
- 27 Sept 2024
- Lead sponsor
- Eli Lilly & Co.
- Diseases
- Obesity
- EU CT number
- 2023-507655-30-00
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 43
- 16 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have had or plan to have a surgical treatment for obesity
Other illness
- Have Type 1 Diabetes
- Have Type 2 Diabetes
- Have history of an inflamed pancreas (pancreatitis)
Who the study is looking for
- Be 12 to 17 years
- Have a BMI equal to or above the 95th percentile for age and sex on CDC-NCHS 2022
Age in the registry: - to 17 years · Sex: All · Does not accept healthy volunteers
Sites (16)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Cologne AöR | Cologne | Germany | Active, not recruiting |
| Universitaetsklinikum Leipzig Aor | Leipzig | Germany | Active, not recruiting |
| Universitaetsklinikum Ulm AoR | Ulm | Germany | Active, not recruiting |
| Hospital Universitari Vall d'Hebron | Barcelona | Spain | Active, not recruiting |
| Hospital Universitario Reina Sofia | Córdoba | Spain | Active, not recruiting |
| Hospital Infantil Universitario Nino Jesus | Madrid | Spain | Active, not recruiting |
| Hospital Universitario Regional de Málaga | Málaga | Spain | Active, not recruiting |
| Hospital Universitario Virgen del Rocío | Sevilla | Spain | Active, not recruiting |
| Hospital Universitario Y Politecnico La Fe | Valencia | Spain | Active, not recruiting |
| Centre Hospitalier Universitaire D'Angers | Angers | France | Active, not recruiting |
| Hospital Femme Mere Enfant | Bron | France | Active, not recruiting |
| Centre Hospitalier Universitaire De Lille | Lille Cedex | France | Active, not recruiting |
| Centre Hospitalier Regional De Marseille | Marseille | France | Active, not recruiting |
| Robert Debre University Hospital | Paris | France | Active, not recruiting |
| Trousseau Hospital | Paris | France | Active, not recruiting |
| Hopital Des Enfants | Toulouse Cedex 9 | France | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.