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2023-507732-20-00Active, not recruitingPhase 3

A randomized double blind, multicenter trial to assess time-interval between cytoreductive surgery and adjuvant chemotherapy after administration of local anesthetic intraperitoneally/perioperatively in advanced epithelial ovarian cancer - IPLA-OVCA

Source: EU CTIS (euclinicaltrials.eu) · Last updated 23 Jan 2026

Next steps

Brief summary (registry, in English)

To investigate whether Ropivacaine 0.2% administered intraperitoneally during surgery and intermittently thereafter for up to 72 h in patients with stage III-IV epithelial ovarian cancer undergoing cytoreductive surgery leads to earlier start of adjuvant chemotherapy.

Status (registry)
Active, not recruiting
Phase (registry)
Phase 3
Study type
Interventional
Enrollment
220 (estimated)
First submitted
18 Aug 2023
Start date
29 Nov 2019
Lead sponsor
Karolinska University Hospital
EU CT number
2023-507732-20-00
EudraCT number
2019-003299-38

What you commit to

  • Study type: Interventional · Phase 3
  • Planned participants: 220
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.

Who cannot take part

Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Allergy to any component drugs used during epidural or intraperitoneal anesthesia (Ropivacaine, Sufentanil)
  • Uncontrolled renal, liver, heart failure or ischemic heart disease
  • Women in whom cytoreductive surgery is not attempted at time of upfront laparotomy due to extent of disease

Other

  • Contraindication to epidural anesthesia
  • Speech, language or cognitive difficulties

Who the study is looking for

  • Women > 18 years
  • ASA I-III
  • Scheduled for upfront cytoreductive surgery for stage III or IV epithelial ovarian cancer
  • Signed written informed consent

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on EU CTIS (euclinicaltrials.eu)

Sites (2)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Lund University HospitalLundSwedenActive, not recruiting
Karolinska University HospitalSolnaSwedenActive, not recruiting

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This page is information, not medical advice. Discuss any trial with your doctor.