2024-518448-20-00CompletedPhase 4
DPDIMP#1-trial: Impact of DPYD gene test on the safety and efficacy of fluoropyrimidine therapy
Source: EU CTIS (euclinicaltrials.eu) · Last updated 29 Oct 2024
Brief summary (registry, in English)
The aims of this study are to investigate the impact of implementation of DPYD gene test on the safety and efficacy of fluoropyrimidine therapy in Finnish patients and to search for novel genetic variants and other individual characteristics associated with the efficacy and safety of cytostatic therapies.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 1000 (actual)
- First submitted
- 16 Oct 2024
- Start date
- 17 Oct 2019
- Lead sponsor
- HUS-Yhtymae
- Diseases
- Colorectal cancer
- EU CT number
- 2024-518448-20-00
- EudraCT number
- 2018-002255-15
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 1000
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindication to planned fluoropyrimidine medication
- Fluoropyrimidine medication as part of chemoradiotherapy
Other
- A person referred to in Sections 7-10 of the Medical Research Act (disabled, a minor, pregnant, breastfeeding or a prisoner)
Who the study is looking for
- Signed informed consent
- Age ≥18 years
- Diagnosed breast cancer or colon cancer, which is treated at Helsinki University Central Hospital Cancer Center, in Oulu University Hospital or in Turku University Central Hospital
- Planned fluoropyrimidine medication
- The result of the DPYD gene test is available before starting fluodopyrimidine medication.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| HUS-Yhtymae | Helsinki | Finland | Completed |
| Oulu University Hospital | Oulu | Finland | Completed |
| Turku University Hospital | Turku | Finland | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.