2024-518528-54-00RecruitingPhase 1
A Phase 1 Study of the Safety and Preliminary Efficacy of CTX112 in Adult Subjects With Refractory Autoimmune Disease.
Source: EU CTIS (euclinicaltrials.eu) · Last updated 17 Aug 2026
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 51 (estimated)
- First submitted
- 20 Dec 2024
- Start date
- 2 Dec 2025
- Lead sponsor
- CRISPR Therapeutics AG
- EU CT number
- 2024-518528-54-00
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 51
- 13 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
AI-kivonat: who the study is looking for
Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults whose autoimmune disease is active and has not responded to treatment: lupus (SLE), systemic sclerosis (SSc) or inflammatory muscle disease (IIM).
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Active systemic lupus erythematosus (SLE), systemic sclerosis (SSc) or idiopathic inflammatory myopathy (IIM).
Read by machine on 9 Nov 2026.
Sites (13)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitaetsklinikum Augsburg | Augsburg | Germany | Recruiting |
| University Hospital Cologne AöR | Cologne | Germany | Recruiting |
| Fraunhofer Institute For Translational Medicine And Pharmacology ITMP | Frankfurt Am Main | Germany | Recruiting |
| Medizinische Hochschule Hannover | Hanover | Germany | Recruiting |
| Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR | Mainz | Germany | Recruiting |
| Hospital Universitario Reina Sofia | Córdoba | Spain | Recruiting |
| Clínica Universidad de navarra | Pamplona | Spain | Recruiting |
| University Hospital Virgen Del Rocio S.L. | Sevilla | Spain | Recruiting |
| Hospital Clinico Universitario de Valencia | Valencia | Spain | Recruiting |
| University Hospital Of Clermont-Ferrand | Clermont-Ferrand | France | Not yet recruiting |
| APHP – Hôpitaux Universitaire Henri Mondor | Créteil | France | Not yet recruiting |
| Centre Hospitalier Universitaire Grenoble Alpes | Grenoble Cedex 9 | France | Not yet recruiting |
| Centre Hospitalier Universitaire De Toulouse | Toulouse Cedex 9 | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.