2024-520131-33-00Not yet recruitingPhase 2
Effect of H2 inhalation therapy on early recurrence after atrial fibrillation ablation.
Effect of H2 inhalation therapy on early recurrence after atrial fibrillation ablation. Multicenter, open-label, randomized phase II controlled trial.
Source: EU CTIS (euclinicaltrials.eu) · Last updated 18 Sept 2026
Brief summary (registry, in English)
To study the efficacy of inhaled hydrogen therapy on early recurrence of atrial fibrillation after ablation and improvement of quality of life at 3 months.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 136 (estimated)
- First submitted
- 28 Oct 2025
- Start date
- 1 Jan 2026
- Lead sponsor
- Centre Hospitalier Universitaire Grenoble Alpes
- Diseases
- Atrial fibrillation
- EU CT number
- 2024-520131-33-00
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 136
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Persons referred to in Articles L1121-5 to L1121-8 of the CSP and Articles 31 to 35 of Regulation 536/2014 (corresponds to all protected persons: pregnant women, women in labor, breastfeeding mothers, persons deprived of their liberty by judicial or administrative decision, persons receiving psychiatric care pursuant to Articles L. 3212-1 and L. 3213-1 who are not covered by the provisions of Article L. 1121-8, persons admitted to a health or social care institution for purposes other than research, minors, persons subject to legal protection measures or unable to give their consent).
Other illness
- Have a history of AF ablation.
Age
- Be over 80 years of age
Other
- Personnel with a hierarchical relationship with the principal investigator
- Have a left atrial diameter ≥ 50 mm on TEE.
- Radiofrequency ablation.
- Patient undergoing long-term anti-inflammatory treatment.
- Patients with gas administration equipment (CPAP, NIV, etc.)
- Women of childbearing potential
- Uncooperative patients
- During exclusion period from another study
Who the study is looking for
- Be over 18 years of age
- Have paroxysmal or persistent AF with symptoms lasting less than 6 months
- Be a candidate for first-time AF ablation (cryoablation, electroporation)
- Understand and agree to comply with the study procedures
- Have a smartphone
- Be enrolled in a social security program or have similar rights
- Have signed the study consent form
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospices Civils de Lyon | Bron | France | Not yet recruiting |
| Centre Hospitalier Universitaire Grenoble Alpes | Grenoble Cedex 9 | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.