2025-520571-66-00RecruitingPhase 3
CYPENZA - A prospective cohort trial on antiandrogens influences on the pharmacokinetics of corticosteroids.
Source: EU CTIS (euclinicaltrials.eu) · Last updated 11 Jun 2026
Brief summary (registry, in English)
To assess the extent to which the antiandrogens (enzalutamide and apalutamide) influence the pharmacokinetics of the administered corticosteroid dexamethasone.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 19 Nov 2025
- Start date
- 30 Jun 2026
- Lead sponsor
- Region Vaesterbotten
- Diseases
- Prostate cancer
- EU CT number
- 2025-520571-66-00
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 30
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with systemic corticosteroids (ongoing or last 4 weeks), inhalations steroids, topical steroids or nasal steroids are not regarded as systemic therapies
- Treatment with health product modulating CYP3A4
- Treatment with warfarin or NOAC (Non-vitamin K-antagonist anticoagulants)
- Previous seizure in medical history
Other illness
- Diabetes (defined as diagnosed diabetes type I or type II)
- Other serious illness or medical condition according to the investigator, e.g., other cancer, history of peptic ulcer, or bipolar disorder.
Who the study is looking for
- Diagnosed prostate cancer
- Intended to begin treatment with antiandrogen therapy, -enzalutamide or apalutamide-
- Can understand all the requirements of the trial, provide informed consent, and provide authorization of use and disclosure of personal health information
- WHO performance status 0-1
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Region Vaesterbotten | Umea | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.