2025-521559-22-00Not yet recruitingPhase 2/3
Pre- and post-treatment evaluation of lung function with Xenon-gas enhanced Dual-Energy CT-imaging in patients undergoing radiotherapy
Source: EU CTIS (euclinicaltrials.eu) · Last updated 5 Feb 2026
Brief summary (registry, in English)
The primary objective of this trial is to acquire high-resolution anatomical and functional information on lung ventilation using a gas mixture of 30 Vol% Xe in 70 Vol% O2 as contrast agent in combination with DECT-imaging in lung and breast cancer patients scheduled to undergo radiotherapy. Ventilation maps will be generated to evaluate the effect of radiotherapy on the lung parenchyma in lung and breast cancer patients.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 1 Aug 2025
- Start date
- 1 Jan 2026
- Lead sponsor
- UZ Brussel
- Diseases
- Lung cancer
- EU CT number
- 2025-521559-22-00
What you commit to
- Study type: Interventional · Phase 2/3
- Planned participants: 40
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Other illness
- No lung or breast cancer having a TNM classification I-IIIa.
- Received prior cancer treatment.
- Patients who are in an unstable condition or who are hospitalized in ICU.
Age
- Younger than 50 or older than 80 years old.
Other
- Cannot perform a 3 s breath hold
- Patients who are suffering from COPD GOLD IV.
- Patients who did not sign informed consent forms.
Who the study is looking for
- Lung and breast cancer having a TNM classification I-IIIa.
- Between 50 and 80 years old.
- No prior cancer treatment.
- Breath hold for 3 seconds
- Patients who are in stable condition or who are not hospitalized in an ICU.
- Patients who are not suffering from COPD GOLD IV.
- Patients who signed informed consent forms.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UZ Brussel | Jette | Belgium | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.