2025-521624-30-00CompletedPhase 2
A Study Evaluating BFB759 in Atopic Dermatitis
A Phase 2, Parallel-arm, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Efficacy and Safety of BFB759 in Patients with Atopic Dermatitis (COMPASS 2-AD)
Source: EU CTIS (euclinicaltrials.eu) · Last updated 28 Sept 2026
Brief summary (registry, in English)
To evaluate the efficacy of BFB759 in adult male and female participants with AD as assessed by Eczema Area and Severity Index (EASI) score
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 116 (actual)
- First submitted
- 15 Jul 2025
- Start date
- 8 Jan 2026
- Lead sponsor
- Bluefin Biomedicine Inc.
- Diseases
- Atopic dermatitis (eczema)
- EU CT number
- 2025-521624-30-00
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 116
- 37 sites in 5 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recently used medications that could interfere with the study.
Other illness
- Have certain infections or other immune conditions.
Other
- Are pregnant or breastfeeding.
Who the study is looking for
- Are adults (18 to 75 years) with a diagnosis of atopic dermatitis for at least one year.
- Have moderate to severe disease not well controlled by topical treatments.
- Are willing to follow study instructions, attend regular visits, and avoid certain other medications during the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (37)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical Center Medconsult Burgas EOOD | Burgas | Bulgaria | Completed |
| Asclepius Medical Center OOD | Dupnitsa | Bulgaria | Completed |
| Medical Center Medconsult Pleven OOD | Lovech | Bulgaria | Completed |
| Medical Center Medconsult Pleven OOD | Pleven | Bulgaria | Completed |
| CCR Ostrava s.r.o. | Moravska Ostrava A Privoz | Czechia | Completed |
| Dermatovenerologicka ordinace MUDr. Blanka Havlickova | Prague | Czechia | Completed |
| Clintrial s.r.o. | Prague 10 | Czechia | Completed |
| Pratia Pardubice a.s. | Prague 4 | Czechia | Completed |
| Thermalsole und Schwefelbad Bentheim GmbH | Bad Bentheim | Germany | Completed |
| CRS Clinical Research Services Management GmbH | Berlin | Germany | Completed |
| Universitaetsklinikum Essen (AoR) | Essen | Germany | Completed |
| Universitaetsmedizin Goettingen | Goettingen | Germany | Completed |
| Universitaetsklinikum Heidelberg AöR | Heidelberg | Germany | Completed |
| Universitaet Muenster | Muenster | Germany | Completed |
| Hospital General Universitario Dr. Balmis | Alicante | Spain | Completed |
| Hospital Universitario Reina Sofia | Córdoba | Spain | Completed |
| Hospital General de Granollers | Granollers | Spain | Completed |
| Grupo Dermatológico y Estético Pedro Jaén S.A | Madrid | Spain | Completed |
| Hospital Clínico San Carlos | Madrid | Spain | Completed |
| Renew Clinic Sp. z o.o. | Bialystok | Poland | Completed |
| Clinicmed Daniluk Nowak Sp. k. | Bialystok | Poland | Completed |
| Centrum Medyczne Kermed Renata Bijata-Bronisz I Ewa Kowalinska Sp. j. | Bydgoszcz | Poland | Completed |
| DERMAPOLIS Medical Dermatology Center dr n. med. Edyta Gębska | Chorzów | Poland | Completed |
| Jagiellonskie Centrum Innowacji Sp. z o.o. | Cracow | Poland | Completed |
| Synexus Polska Sp z o.o. | Gdansk | Poland | Completed |
| Penta Hospitals Badania Kliniczne sp. z o.o. | Gdansk | Poland | Completed |
| Centrum Badawcze Panaceum Agnieszka Brzezicka Magdalena Lenkiewicz Sp. z o. o | Malbork | Poland | Completed |
| Dermedic Jacek Zdybski | Ostrowiec Świętokrzyski | Poland | Completed |
| EMC Instytut Medyczny S.A. | Poznan | Poland | Completed |
| Twoja Przychodnia Poznanskie Centrum Medyczne Sp. z o.o. | Poznan | Poland | Completed |
| Mcbk s.c. Iwona Czajkowska Anna Podrazka Szczepaniak | Pruszkow | Poland | Completed |
| Centrum Zdrowia Dziecka i Rodziny im Jana Pawla II w Sosnowcu Sp z o o | Sosnowiec | Poland | Completed |
| Medicover Integrated Clinical Services Sp. z o.o. | Torun | Poland | Completed |
| Manufaktura Urody Sp. z o.o. | Warsaw | Poland | Completed |
| Therapia Nova Sp z o.o | Warsaw | Poland | Completed |
| Prywatna Praktyka Lekarska Ewa Ring | Warszawa | Poland | Completed |
| Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu | Wroclaw | Poland | Completed |
This page is information, not medical advice. Discuss any trial with your doctor.