2025-522136-14-00Not yet recruitingPhase 4
Antibiotic Treatment Trial in Acute Coronary Syndrome
Source: EU CTIS (euclinicaltrials.eu) · Last updated 27 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
To assess whether the number of clinical endpoints (MACCE) can be reduced by antibiotic treatment, targeting mainly bacteria that have in previous studies been shown to be involved in complex atherosclerotic plaques, such as those found in patients suffering from acute myocardial infarction.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 1070 (estimated)
- First submitted
- 11 Jun 2025
- Start date
- 1 Nov 2025
- Lead sponsor
- TAYS Sydaenkeskus Oy
- Diseases
- Coronary artery disease
- EU CT number
- 2025-522136-14-00
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 1070
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- On-going methotrexate medication
- On-going antibiotic therapy
Other illness
- Clinical diagnosis of Takotsubo syndrome
- Severe valvular disease
- On-going bleeding or very high bleeding risk
- Severe allergy to contrast agents or ASA
- Allergy to cephalosporin
Other
- Cardiogenic shock
- Pregnancy
- Probable finding of SCAD (spontaneous coronary dissection)
- Definite coronary embolism
- < 1 year life expectancy
Who the study is looking for
- Clinically diagnosed ST-elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction (NSTEMI)
- Invasive strategy has been chosen, i.e. angiography is performed
- Age ≥18 years
- Informed consent has been obtained
- at least 3 of following high risk criteria are met (hypertension, DM, moderate renal insufficiency eGFR<60ml/min, peripheral arterial disease ASO, multivessel coronary artery disease, previous myocardial infraction, previous stroke or TIA)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| TAYS Sydaenkeskus Oy | Tampere | Finland | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.