2025-523207-29-00RecruitingPhase 4
Evaluation of postoperative recovery when combining intravenous lidocaine with ropivacaine infiltration in laparoscopic colorectal oncologic surgery: a randomized controlled trial
Source: EU CTIS (euclinicaltrials.eu) · Last updated 22 Sept 2026
Brief summary (registry, in English)
Evaluate the effectiveness of combining intravenous lidocaine and ropivacaine infiltration of laparoscopic trocar sites on postoperative recovery as assessed using the QOR-15 twenty-four hours after colorectal surgery.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 182 (estimated)
- First submitted
- 15 Sept 2025
- Start date
- 24 Apr 2026
- Lead sponsor
- Centre Hospitalier Universitaire Amiens Picardie
- Diseases
- Colorectal cancer
- EU CT number
- 2025-523207-29-00
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 182
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
AI-kivonat: who the study is looking for
Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults having planned keyhole (laparoscopic) surgery for colorectal cancer. It tests IV lidocaine plus ropivacaine at the cut sites for recovery.
- Age
- 18 years or older
- Sex
- All sexes
- Disease stage
- Colorectal cancer, scheduled for laparoscopic surgery.
- Earlier treatment
- People who used opioids or opioid-like drugs before surgery cannot join.
Main reasons for not taking part
- Allergy or contraindication to lidocaine, ropivacaine or the other listed drugs
- Surgery by open cut (laparotomy), or surgery not for cancer
- Chronic pain lasting more than 3 months
- Psychiatric disorders
- Pregnant or breastfeeding women
Read by machine on 9 Nov 2026.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Colorectal surgery by laparotomy
Other illness
- Allergy or contraindication to lidocaine or ropivacaine,
- Allergy or contraindication to paracetamol, nefopam, ketamine, propofol, dexamethasone, sufentanil , Celebrex or Parecoxib, , morphine derivatives, and Colorectal surgery by laparotomy
- Colorectal surgery not indicated for cancer treatment
- Patients suffering from psychiatric disorders
Other
- Patients under guardianship, conservatorship, or legal protection
- Chronic preoperative pain (defined as pain persisting for more than 3 months),
- Preoperative use of opioids or opioid derivatives,
- Patients for whom pain self-assessment using a self-assessment scale cannot be performed (non-communicative, non-English-speaking, etc.)
- Pregnant or breastfeeding women
Who the study is looking for
- Patients undergoing scheduled laparoscopic colorectal cancer surgery.
- Patients aged 18 years or older
- Highly effective method of contraception for women of childbearing age (combined hormonal contraception (estrogen and progesterone) combined with ovulation inhibition (oral, intravaginal, transdermal), hormonal contraception (progesterone only) combined with ovulation inhibition (oral, injectable, implantable), intrauterine device, intrauterine hormone-releasing system, bilateral fallopian tube occlusion, vasectomized partner, sexual abstinence.
- Informed consent and signed agreement
- Enrollment in a Social Security plan
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier Universitaire Amiens Picardie | Amiens Cedex 1 | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.