2025-523781-25-00RecruitingPhase 1
PHASE 1 STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND IMMUNOGENICITY OF E-VIM VACCINE CVX1 WITH OR WITHOUT ICI IN THE TREATMENT OF SUBJECTS WITH MUSCLE INVASIVE BLADDER CANCER (MIBC) OR LOCALIZED OR LOCALLY ADVANCED RENAL CELL CANCER (RCC).
Source: EU CTIS (euclinicaltrials.eu) · Last updated 14 Sept 2026
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 83 (estimated)
- First submitted
- 10 Nov 2025
- Start date
- 2 Apr 2026
- Lead sponsor
- CimCure B.V.
- Diseases
- Bladder cancer
- EU CT number
- 2025-523781-25-00
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 83
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
AI-kivonat: who the study is looking for
Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with muscle invasive bladder cancer or localized or locally advanced kidney cancer (renal cell cancer). It tests the safety of the E-VIM vaccine CVX1, with or without an immune checkpoint inhibitor (ICI).
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Muscle invasive bladder cancer, or localized or locally advanced renal cell cancer (RCC)
Read by machine on 9 Nov 2026.
Sites (4)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Netherlands Cancer Institute | Amsterdam | Netherlands | Recruiting |
| Amsterdam UMC Stichting | Amsterdam | Netherlands | Recruiting |
| Leids Universitair Medisch Centrum (LUMC) | Leiden | Netherlands | Recruiting |
| Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC) | Rotterdam | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.