2026-526241-98-00Not yet recruitingPhase 2
A Long-term Study of KT-621 Administered Orally to Participants with Asthma Previously Enrolled in a KT-621 Asthma Study
A Multicenter, Open-Label, Long-Term Extension Study to Evaluate the Long Term Safety and Tolerability of KT-621 in Participants With Asthma Previously Enrolled in a KT-621 Asthma Study
Source: EU CTIS (euclinicaltrials.eu) · Last updated 23 Sept 2026
Brief summary (registry, in English)
To evaluate the long-term safety and tolerability of KT-621 in participants with asthma
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 77 (estimated)
- First submitted
- 5 Jun 2026
- Start date
- 1 Sept 2026
- Lead sponsor
- Kymera Therapeutics Inc.
- Diseases
- Asthma
- EU CT number
- 2026-526241-98-00
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 77
- 41 sites in 8 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
AI-kivonat: who the study is looking for
Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with asthma who finished an earlier KT-621 asthma study. It checks the long-term safety of the pill KT-621.
- Age
- 18 years and older
- Sex
- All sexes can join.
- Disease stage
- Uncontrolled moderate to severe eosinophilic asthma.
- Earlier treatment
- Must have completed all visits of the earlier KT-621 asthma study, up to the end of treatment visit. Must not have stopped study treatment for good in that study.
Main reasons for not taking part
- Clinically significant change in health during the earlier study that could affect safety or study visits
- Side effect in the earlier study that could make continued treatment an unreasonable risk
- Study treatment permanently stopped in the earlier study
- Member of the sponsor's or site's study team, or their immediate family
- Any other reason the investigator judges unsuitable, including likely not following study procedures
Read by machine on 9 Nov 2026.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Other
- Must not have experienced any clinically significant change in health status during the parent study, which, in the opinion of the Investigator, would interfere with participant safety, study evaluations, or compliance with study procedures; or otherwise make the participant unsuitable for participation in this study.
- Must not have developed an AE during the parent study, that in the opinion of the Investigator or of the Sponsor's Medical Monitor, could indicate that continued treatment may present an unreasonable risk for the participant.
- Must not have met permanent discontinuation criteria and/or permanently discontinued study treatment for any reason during the parent study.
- Must not be a member of the Sponsor or site's investigational team or their immediate family.
- Must not be unsuitable to enter the study for any other reason, as judged by the Investigator, including potential risk of noncompliance to study procedures.
Who the study is looking for
- Must have completed all visits of the parent study, per its protocol, up to the end of treatment (EoT) visit.
- Must be willing and able to comply with scheduled visits, treatment plan, laboratory tests, other study-related procedures, and questionnaires, including completing the electronic diary (e-diary), for the duration of the study as required by the study protocol.
- Must agree to contraceptive requirements in compliance with the clinical study and local requirements.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (41)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of Vienna | Vienna | Austria | Not yet recruiting |
| Klinik Hietzing | Vienna | Austria | Not yet recruiting |
| CHU Saint-Pierre | Brussels | Belgium | Not yet recruiting |
| Az Maria Middelares Gent | Gent | Belgium | Not yet recruiting |
| Centre Hospitalier Regional de la Citadelle | Liège | Belgium | Not yet recruiting |
| Pneumocare | Namur | Belgium | Not yet recruiting |
| Cliniques Universitaires Saint-Luc | Sint-Lambrechts-Woluwe | Belgium | Not yet recruiting |
| Lungenpraxis Hohenzollerndamm | Berlin | Germany | Not yet recruiting |
| Berufsausuebungsgemeinschaft Bag Prof. Dr. Med Gerhard Hoheisel Dr. Med Andreas Bonitz GbR | Leipzig | Germany | Not yet recruiting |
| POIS Sachsen GmbH | Leipzig | Germany | Not yet recruiting |
| Hospital Universitario Puerta del Mar | Cadiz | Spain | Not yet recruiting |
| Hospital de Jerez de la Frontera | Jerez de la Frontera | Spain | Not yet recruiting |
| Hospital Universitario 12 de Octubre | Madrid | Spain | Not yet recruiting |
| Hospital Universitario Infanta Leonor | Madrid | Spain | Not yet recruiting |
| Clinica Respira-Dr.Juanola | Mataro | Spain | Not yet recruiting |
| University Hospital Of Canary Islands | San Cristobal De La Laguna | Spain | Not yet recruiting |
| Hospital Universitario Marqués de Valdecilla | Santander | Spain | Not yet recruiting |
| Azienda Universitaria Ospedaliera Consorziale Policlinico Bari | Bari | Italy | Not yet recruiting |
| IRCCS Azienda Ospedaliera Metropolitana | Genoa | Italy | Not yet recruiting |
| Azienda Socio Sanitaria Territoriale Santi Paolo E Carlo | Milan | Italy | Not yet recruiting |
| Azienda Ospedaliera dei Colli | Naples | Italy | Not yet recruiting |
| Azienda Ospedaliera Policlinico Universitario Tor Vergata | Rome | Italy | Not yet recruiting |
| Azienda Ospedaliero-Universitaria Sant Andre | Rome | Italy | Not yet recruiting |
| Bio Zdrowie Sp. z o.o. | Bialystok | Poland | Not yet recruiting |
| Homeo Medicus Szczesiul sp.j. | Bialystok | Poland | Not yet recruiting |
| Clinica Vitae Sp. z o.o. | Gdansk | Poland | Not yet recruiting |
| Samodzielny Publiczny Zaklad Opieki Zdrowotnej Uniwersytecki Szpital Kliniczny Nr 1 Im. Norberta Barlickiego Uniwersytetu Medycznego W Lodzi | Lodz | Poland | Not yet recruiting |
| Umed Clinical Trials Sp. z o.o. | Lodz | Poland | Not yet recruiting |
| Santa Familia PTG Łódź | Łódź | Poland | Not yet recruiting |
| Alergologia Plus sp. z o.o. | Poznan | Poland | Not yet recruiting |
| Kiepury Clinic Malgorzata Jarnot Specjalistyczna Praktyka Ginekologiczno-Położnicza | Sosnowiec | Poland | Not yet recruiting |
| CenterMed Sp. z o.o. | Tarnów | Poland | Not yet recruiting |
| Viltis Medica Sp. Z o.o. | Trzebnica | Poland | Not yet recruiting |
| Lekarze Specjalisci - J. Malolepszy I Partnerzy | Wroclaw | Poland | Not yet recruiting |
| Centrum Medyczne Lucyna Andrzej Dymek s.c. | Zawadzkie | Poland | Not yet recruiting |
| Theramed Healthcare S.R.L. | Brasov | Romania | Not yet recruiting |
| Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie "Victor Babeș" Craiova | Craiova | Romania | Not yet recruiting |
| Neoclinic Concept S.R.L. | Timisoara | Romania | Not yet recruiting |
| ALIAN s.r.o. | Bardejov | Slovakia | Not yet recruiting |
| Alersa s.r.o. | Košice | Slovakia | Not yet recruiting |
| Plucna ambulancia Hrebenar S.R.O. | Spišská Nová Ves | Slovakia | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.