2026-526869-19-00Not yet recruitingPhase 4
PREconception weight management Programme to Achieve weight Reduction and Enhance fertility (PREPARE)
A feasibility randomised controlled trial of a weight management programme for women living with obesity and infertility
Source: EU CTIS (euclinicaltrials.eu) · Last updated 30 Oct 2026
Brief summary (registry, in English)
The primary objective is to assess the feasibility and acceptability of combining pharmacotherapy with a digitally delivered behaviour change intervention, compared with behaviour change alone, to support weight loss and improve fertility in women living with obesity and infertility.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 21 Jul 2026
- Start date
- 2 Nov 2026
- Lead sponsor
- University College Dublin
- Diseases
- Obesity
- EU CT number
- 2026-526869-19-00
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 60
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study design.
AI-kivonat: who the study is looking for
Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women with obesity who have had trouble getting pregnant. It tests a weight loss medicine plus a digital programme against the digital programme alone.
- Age
- Women aged 18-39 years
- Sex
- Women only
- Disease stage
- BMI 30-40 kg/m2. Trying to conceive for more than 12 months if under 36 years old, or more than 6 months if 36 or older.
- Earlier treatment
- Fertility assessments completed within the previous 6 months.
Main reasons for not taking part
- Currently pregnant or breastfeeding
- Known allergy or reason not to take the trial medicine
- Taking part in another trial of a medicine
- Unwilling or unable to give informed consent
Read by machine on 9 Nov 2026.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent participation in another investigational medicinal product study, although participants will not be excluded from other observational studies provided the other observational studies have no interventions.
Other illness
- Known hypersensitivity or contraindication to the intervention medication
Other
- Current pregnancy or breastfeeding
- Unwilling or unable to give informed consent
Who the study is looking for
- Women aged 18-39 years
- BMI 30-40 kg/m2
- Trying to conceive for > 12 months if under 36 years of age, or for > 6 months if aged 36 years of age or over and have had fertility assessments completed within the previous 6 months
- Meet the following HSE criteria for fertility treatment
- Agreeable to contraceptive use if allocated to the intervention group
- Meet study eligibility criteria
- Willing and able to give informed consent
Age in the registry: 18 years to 64 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St Vincent's University Hospital | Dublin 4 | Ireland | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.