NCT00060541Recruiting
Evaluation and Treatment of Neurosurgical Disorders
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
Objective: This protocol is designed to allow the Surgical Neurology Branch to evaluate and treat the neurosurgical disorders of protocol participants. The participants will receive standard-of-clinical-care evaluation and treatment. The clinical data and samples generated during standard of care treatment will be collected as part of this study. Study Population: Participants 4 years of age and older with neurosurgical-related conditions, who are seeking care from or referred to the Surgical Neurology Branch for evaluation, are eligible for this protocol. Study Design: This is an observational study. Participants will receive standard-of-clinical-care evaluation and treatment for their neurosurgical condition. Clinical evaluation may include laboratory and radiological studies designed to aid in diagnosis or differential diagnosis of the participant s condition or to facilitate treatment. The evaluations may take place in the outpatient clinic areas or in the inpatient units. Some participants will receive standard-of-care medical or surgical treatment for their disorder. Clinical data, tissue samples or body fluids obtained during standard of care treatment, may be used for research. Additional genetic testing may be performed on subjects and their blood relatives if a genetic mechanism underlying the neurological disorder is suspected. Patients in this study may choose to consent to skin biopsies for research purposes, in which case they will sign an additional consent document for this research procedure. Outcome Measures: No additional research outcome measures will be tracked in this study, as this study is collecting data for potential future use. All outcomes will be those of standard clinical evaluation and treatment. A clinical and research database will be kept of patient s diagnosis, progression, and treatment. Clinical database information may be reported or be used in other studies. ...
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 5000 (estimated)
- First submitted
- 7 May 2003
- Start date
- 4 Jun 2003
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- Diseases
- Epilepsy, Parkinson disease, Childhood cancers
- NCT number
- NCT00060541
What you commit to
- Study type: Observational
- Planned participants: 5000
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- 1\. Patients who are unable to undergo evaluation and treatment for a neurosurgical disorder
- Participants must seek care from or be referred to the Surgical Neurology Branch for evaluation and management of neurosurgical conditions (such as central nervous system tumors, peripheral nerve tumors, epilepsy, Parkinson s disease, movement disorders, Chiari syndrome, central nervous system malformations, and pain disorders)
- Patients who are unable to undergo evaluation and treatment for a neurosurgical disorder
- At the time of enrollment, subjects without an established diagnosis of a wellcharacterized disease entity with validated treatment algorithms. In such cases, proposed resource investment, in the opinion of the investigators, would not contribute to further advancement of knowledge
Age
- Participants must be age 4 and older.
Other
- 3.c. Participant Inclusion Criteria for the cohort with processing of biological samples only (for those subjects who are only having skin biopsies and/or saliva samples)
- For adults: able to provide informed consent or having a legally-authorized representative to provide consent, if incapacitated
- For minors: a parent or legal guardian who is able to provide consent.
- Be willing to consent for collection of clinical data or biological samples or their cryopreservation
- 3.D. Participant Exclusion Criteria for the cohort with processing of biological samples only (for those subjects who are only having skin biopsies and/or saliva samples)
Criteria the registry did not label
- INCLUSION CRITERIA:
- Participants must be age 4 and older.
- Participants must seek care from, or be referred to the Surgical Neurology Branch for evaluation and management of neurosurgical conditions (such as central nervous system tumors, peripheral nerve tumors, epilepsy, Parkinson s disease, movement disorders, Chiari syndrome, central nervous system malformations, and pain disorders)
- For adults: able to provide informed consent or having a legally-authorized representative to provide consent, if incapacitated
- For minors: a parent or legal guardian who is able to provide consent.
- For immediate blood relatives of subjects having genetic testing only:
- Blood relative of a subject who is suspected to have a genetic mechanism underlying their neurological disorder (for genetic testing only).
Age in the registry: 4 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Institutes of Health Clinical Center Coordinator of this site? Confirm its status | Bethesda | United States | Recruiting |
Related publications
- Intralabyrinthine MRI FLAIR as a predictive marker for hearing loss in vestibular schwannomas in Neurofibromatosis Type 2.J Neurooncol · 2026 · PMID 41586863
This page is information, not medical advice. Discuss any trial with your doctor.