NCT00084292Recruiting
Database for Stroke in Infants and Children: the International Pediatric Stroke Study
International Pediatric Stroke Study
Source: ClinicalTrials.gov · Last updated 15 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The International Pediatric Stroke Study (IPSS) was established in 2003 as a multi-center, multi-national clinical research registry. Over the years, it has grown to become a highly successful study vehicle for pediatric stroke research across over 100 institutions worldwide. Today, The IPSS continues to serve as the global clinical data and imaging core for multi-disciplinary pediatric experts who perform international collaborative research to better understand, prevent, and improve outcomes in pediatric stroke. The robust dataset and cohesive network enable high caliber and ground-breaking research in the field. Participating sites enroll neonates or children who have had an ischemic or hemorrhagic stroke, or may be at high risk of having a stroke. Participants have their medical and research records reviewed for information about their stroke and abstracted into a secure electronic database called REDCap, which is hosted at SickKids in Toronto Canada. The IPSS also provides an attractive imaging platform (through the Stroke Imaging Lab for Children, SILC, housed at SickKids) for sites to share clinically acquired brain images that will complement the clinical dataset. The clinical and imaging datasets will improve our understanding of the processes underlying plasticity and recovery in childhood stroke.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 12000 (estimated)
- First submitted
- 9 Jun 2004
- Start date
- Jan 2003
- Primary completion date
- Dec 2030
- Lead sponsor
- The Hospital for Sick Children
- Diseases
- Stroke
- NCT number
- NCT00084292
What you commit to
- Study type: Observational
- Planned participants: 12000
- From Jan 2003 to the primary completion date, Dec 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Brain hemorrhage secondary to trauma
Other
- Premature children diagnosed with AIS.
- Premature children diagnosed with PPIS
- Children diagnosed with TIA (Transient Ischemic Attack)
- Refusal to provide consent for participation
Who the study is looking for
- This registry will include all children from birth to 18 years of age who are diagnosed with stroke or a condition/disease (as defined below) that put them at high risk of stroke after Jan 1,2003 at one of the IPSS participating sites.
- This registry will include children diagnosed with below stroke types:
- Arterial Ischemic Stroke (AIS),
- Cerebral Sinovenous Thrombosis (CSVT),
- AIS and CSVT
- Presume Preinatal Ischemic Stroke (PPIS)
- Children diagnosed with hemorrhagic stroke
- Children at high risk of stroke include:
- Those diagnosed with arteriopathy, arteritis/vasculitis, moyamoya, dissection, sickle cell related infarcts).
- Brain arteriovenous malformations
Age in the registry: - to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital for Sick Children Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.