NCT00114881Completed
Urban Environmental Factors and Childhood Asthma
Urban Environment and Childhood Asthma (URECA)
Source: ClinicalTrials.gov · Last updated 18 Jul 2025
Brief summary (registry, in English)
Minority children who grow up in poor urban neighborhoods have the highest rates of asthma, and also experience greater morbidity from acute exacerbations of this disease. The aim of this study is to further identify environmental factors unique to the inner city that affect immune development and the expression of wheezing, atopy and asthma for purposes of identifying new strategies for asthma prevention.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 560 (actual)
- First submitted
- 17 Jun 2005
- Start date
- 2 Feb 2005
- Primary completion date
- 31 Aug 2024
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- Diseases
- Asthma
- NCT number
- NCT00114881
What you commit to
- Study type: Observational
- Participants enrolled: 560
- From 2 Feb 2005 to the primary completion date, 31 Aug 2024
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Received palivizumab for respiratory syncytial virus prophylaxis
Other illness
- HIV infected at the time of delivery
Other
- Plan to move out of the geographic area during the study
- Respiratory distress requiring intubation and ventilation for 4 hours or more
- Respiratory distress requiring either supplemental oxygen or continuous positive airway pressure (CPAP) for 4 days or more
- Pneumonia requiring antibiotic treatment for 1 week or more
- Significant congenital abnormality
Who the study is looking for
- Plan to give birth at the study hospital
- Have asthma, hay fever, or eczema (or infant's father has any of these diseases)
- Currently reside in a pre-selected area containing at least 20% of households below the U.S. government poverty level
- At least 34 weeks pregnant at time of delivery
- Willing to allow an umbilical cord blood specimen to be obtained from her infant
- Willing to comply with all study requirements
- Have access to a phone
- Speak English. Spanish-speaking participants enrolled at sites with Spanish-speaking staff are also eligible.
Sex: All · Accepts healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pediatric Clinical Research Unit, Johns Hopkins University Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| Boston Medical Center Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Columbia University Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Saint Louis Children's Hospital Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.