NCT00181259Recruiting
Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
In Vivo Cardiac Metabolism in Normal, Ischemic, and Cardiomyopathic Patients During Rest and Stress
Source: ClinicalTrials.gov · Last updated 9 Mar 2026
Brief summary (registry, in English)
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 13 Sept 2005
- Start date
- Jan 1988
- Primary completion date
- Aug 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- Heart failure
- NCT number
- NCT00181259
What you commit to
- Study type: Observational
- Planned participants: 500
- From Jan 1988 to the primary completion date, Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- contraindication to MRI
Who the study is looking for
- age \> 18 years
- Healthy subjects: no history of heart disease
- Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) \<40%
- Left ventricular hypertrophy: wall thickness \>1.2cm
- Coronary artery disease: \>50% coronary lesion or positive stress test
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins Medical Institutions Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.