NCT00431756Active, not recruiting
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus (Previously: Methylation in Cancer Progression of Barrett's Esophagus
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to determine if there are any early changes in DNA markers of blood and esophageal tissue in people with gastric reflux, Barrett's esophagus or esophageal cancer that can warn of a progression to esophageal cancer.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 2 Feb 2007
- Start date
- 1 May 2002
- Primary completion date
- 1 May 2023
- Lead sponsor
- Johns Hopkins University
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT00431756
What you commit to
- Study type: Observational
- Planned participants: 600
- From 1 May 2002 to the primary completion date, 1 May 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- People who are are currently having chemotherapy, or who have completed chemotherapy within the last 4 weeks.
- People who have ever had radiation treatments to their chest.
Who the study is looking for
- People who are undergoing upper endoscopy as part of their medical care with a history of esophageal cancer, Barrett's esophagus, or upper gastrointestinal symptoms.
Age in the registry: 18 years to 95 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins Hospital Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.