NCT00496119Active, not recruitingPhase 2
Proton Beam Therapy for Chordoma Patients
Phase II Evaluation of Proton Beam Therapy for Skull Base Chordoma
Source: ClinicalTrials.gov · Last updated 12 Jun 2026
Brief summary (registry, in English)
The goal of this clinical research study is to learn if proton beam therapy, with or without photon beam radiation therapy, is effective in the treatment of skull base chordoma. The safety of this treatment will also be studied.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 19 (actual)
- First submitted
- 2 Jul 2007
- Start date
- 18 Sept 2006
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- M.D. Anderson Cancer Center
- NCT number
- NCT00496119
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 19
- From 18 Sept 2006 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous irradiation of the skull base
- Any concurrent malignancy (other than non-melanoma skin cancers) in the last 3 years
Other illness
- Documented evidence of disseminated metastatic disease
Who the study is looking for
- Pathologically confirmed chordoma of the skull base
- Contrast enhanced postoperative MRI (CT in case MRI is contraindicated) of the skull base obtained within 90 days of study registration
- MDACC surgeons have determined that optimal debulking of disease has been performed.
- Karnofsky Performance status greater than or equal to 60
- Signed informed consent
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas - MD Anderson Cancer Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.