NCT00582881Completed
Characteristics and Disease Progression of Mixed Connective Tissue Disease and Systemic Lupus Erythematosus
Immune Response to Small Nuclear Ribonucleoprotein Autoantigens
Source: ClinicalTrials.gov · Last updated 19 Mar 2026
Brief summary (registry, in English)
Systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD) are long-term autoimmune diseases in which the immune system attacks parts of the body. The abnormal immune reaction causes inflammation of and damage to various body parts and can affect joints, skin, kidneys, heart, lungs, blood vessels, and the brain. SLE and MCTD often affect young women, especially black and Hispanic women, and there is no known cure. Knowing more about SLE and MCTD will help in developing new and effective treatments. The purpose of this study is to characterize immune system abnormalities, genetic components, and disease progression in people with SLE and MCTD.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 124 (actual)
- First submitted
- 19 Dec 2007
- Start date
- Oct 2007
- Primary completion date
- 27 Jun 2025
- Lead sponsor
- University of Miami
- Diseases
- Lupus (SLE)
- NCT number
- NCT00582881
What you commit to
- Study type: Observational
- Participants enrolled: 124
- From Oct 2007 to the primary completion date, 27 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Poor venous access, unstable medical problems or significant cardiopulmonary disease, anemia, leukopenia, thrombocytopenia, anticoagulation therapy, recent significant changes in medication or pregnacy. Patient cannot be taking large dose of corticosteroids (above 30mg per day) or cytotoxic drugs (cyclophosphamide, azathiprine, cyclosporine, methotrexate).
Who the study is looking for
- Patients with known rheumatic diseases including systemic lupus erythematosus, rheumatoid arthritis, connective tissue disease, undifferentiated connective tissue disease
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Miami Miller School of Medicine Coordinator of this site? Confirm its status | Miami | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.