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NCT00591500Active, not recruiting

A Model for Genetic Susceptibility: Melanoma

Source: ClinicalTrials.gov · Last updated 5 Aug 2026

Brief summary (registry, in English)

The goal of this study is to find out if some people are more likely to get melanoma, a form of skin cancer, than others are. To do this we will compare people who have had more than one melanoma to people who have had only one melanoma and to people who are similar but who have not developed melanoma. People respond to the environment in different ways. Some may be born with genes that make them more likely to get this type of skin cancer. Each person has many ways to repair normal damage to their genes. Specific genes may affect the repair of sun damage. Other genes affect the way the skin itself reacts to the sun. We want to find out which genes have normal changes in them and lead to different responses to exposures, such as the sun. We also want to find out if sun habits are related to the way these genes work.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
4082 (actual)
First submitted
26 Dec 2007
Start date
Nov 1999
Primary completion date
Jul 2027
Lead sponsor
Memorial Sloan Kettering Cancer Center
NCT number
NCT00591500

What you commit to

  • Study type: Observational
  • Participants enrolled: 4082
  • From Nov 1999 to the primary completion date, Jul 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Subjects who do not speak English or Italian
  • Subject is unable to sign informed consent
  • Subject is unable to participate in telephone interview

Who the study is looking for

  • \- The subject must have a histologically confirmed invasive first primary melanoma newly diagnosed between January 1, 2000 and December 31, 2000.
  • OR the subject must have a histologically confirmed invasive or in situ second primary melanoma newly diagnosed between January 1, 1998 and December 31, 2003. One of the earlier primaries must be invasive melanoma OR the subject must be a randomly ascertained control from the general.
  • \- The patient must be a resident of a one of the specific geographic areas participating in this study.

Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Memorial Sloan-Kettering Cancer Center
Coordinator of this site? Confirm its status
New YorkUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.