NCT00593840Active, not recruitingPhase 2
Phase II Trial Evaluating Elimination of Radiation Therapy
Phase II Trial Evaluating Elimination of Radiation Therapy To Pathological N0 Neck(s) With Intensity Modulated Postoperative Radiation Therapy
Source: ClinicalTrials.gov · Last updated 29 Jul 2026
Brief summary (registry, in English)
The purpose of this study is to determine if reducing or eliminating radiation treatment to one or both sides of the neck where there is no evidence of cancer can help spare the side effects of radiation treatment for head and neck cancer. In this study, the investigators plan to reduce the amount of radiation treatment received to healthy tissue
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 74 (actual)
- First submitted
- 2 Jan 2008
- Start date
- 11 Apr 2007
- Primary completion date
- 28 Feb 2014
- Lead sponsor
- Washington University School of Medicine
- Diseases
- Head and neck cancer
- NCT number
- NCT00593840
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 74
- From 11 Apr 2007 to the primary completion date, 28 Feb 2014
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous head and neck cancer other than non melanoma skin cancer.
- Previous head and neck surgery.
Other
- Female patients who are pregnant or nursing.
Who the study is looking for
- Patients with pathologically proven tumors of the oral cavity, oropharynx, larynx, or hypopharynx .
- Treated with surgical resection with one (or both) side(s) of the neck pathologically N0.
- Indication for radiation therapy at the primary site or neck consisting of any of the below characteristics:
- Close margin (\<= 0.5 cm)
- Positive margin
- Perineural invasion
- Lymphovascular space invasion
- Metastatic disease in more than one lymph node
- Metastatic disease in more than one lymph node group
- Extracapsular extension in any lymph node
- Constellation of factors considered to be at risk based on the multi-disciplinary tumor board discussion.
- Age \>= 18.
- Patients must sign study specific, Institutional Review Board (IRB)-approved consent form.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Washington University School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.