NCT00597636Active, not recruiting
Genetic Susceptibility to Lung Cancer in Never Smokers
Source: ClinicalTrials.gov · Last updated 11 Jun 2026
Brief summary (registry, in English)
The purpose of this study is to help us better understand the cellular changes that may lead to the development of lung cancer. We want to compare people who have never smoked and yet have been diagnosed with lung cancer to never smokers who have not developed lung cancer. We hope to use the information obtained in this study as the basis for future studies and will not regard the results from this study as final.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 238 (actual)
- First submitted
- 10 Jan 2008
- Start date
- Jun 2005
- Primary completion date
- Jun 2027
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Diseases
- Lung cancer, Childhood cancers
- NCT number
- NCT00597636
What you commit to
- Study type: Observational
- Participants enrolled: 238
- From Jun 2005 to the primary completion date, Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- All individuals who otherwise meet the eligibility requirements above, but who have had chemotherapy or radiation therapy within 1 year of evaluation will be excluded (Exception: genotyping analysis/screening can be performed on specimens from individuals who had chemo/radiation treatment within the last year as germline DNA will not be affected).
Other
- Subjects who do not meet the inclusion criteria for either the case or control groups will not be eligible for this study.
Who the study is looking for
- Cases will be eligible for inclusion if:
- They have been diagnosed with a lung cancer or have had previous surgical treatment for their lung cancer and have smoked fewer than 100 cigarettes in their lifetime, are/were not regular cigar or pipe smokers, and
- They have had no prior chemotherapy or radiation treatment within the last year (Exception: genotyping analysis/screening can be performed on specimens from individuals who had chemo/radiation treatment within the last year as germline DNA will not be affected)
- They speak and read English
- They understand and agree to sign informed consent, and
- They agree to give us a blood sample, and
- They agree to complete the study questionnaire, and
- They agree to have their pathology information reviewed by study personnel.
- Controls will be eligible for inclusion if:
- They have not been diagnosed with any type of cancer, exclusive of nonmelanoma skin cancer and have smoked fewer than 100 cigarettes in their lifetime, are/were not regular cigar or pipe smokers, and
- They speak and read English
- They understand and agree to sign informed consent, and
- They agree to give us a blood sample, and
- They agree to complete the study questionnaire.
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Memorial Sloan-Kettering Cancer Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.