NCT00762008Recruiting
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
Source: ClinicalTrials.gov · Last updated 17 Aug 2026
Brief summary (registry, in English)
The purpose of this research is to determine if two proteins in the blood are increased during acute heart failure. These two proteins are produced when the heart becomes dysfunctional and unable to contract normally. They may then be released into the blood and be detected by standard method in the research laboratory. Thus, the purpose of this study is to determine the relation between the change of these two proteins in the blood and the occurrence of acute heart failure. At this time, detection of an increase in these proteins in the blood is not known to be associated with any disease or heart failure.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 26 Sept 2008
- Start date
- 1 Dec 2005
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- UConn Health
- Diseases
- Heart failure
- NCT number
- NCT00762008
What you commit to
- Study type: Observational
- Planned participants: 500
- From 1 Dec 2005 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subjects who had undergone cardiac or non-cardiac surgery in the 3 months before enrollment
Other
- Subjects who are unable to give informed consent
- Pregnant subjects are not excluded
Who the study is looking for
- Individuals aged \>18yrs
- stable or decompensated heart failure, irrespective of LVEF
- decompensated heart failure clinical symptoms such as dyspnea, rales, edema, elevated jugular venous pressure, or ascites
- Imaging evidence of heart failure (cardiomegaly, poor contractile function or echocardiographic Doppler evidence of diastolic dysfunction or elevated right- or left-sided filling pressures)
- Healthy individuals with no prior history of heart attack or heart failure will be recruited to use as controls.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Connecticut Health Center Coordinator of this site? Confirm its status | Farmington | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.