NCT00766584Active, not recruiting
Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea
Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea in a Prospective Cohort of Subjects Aged 67 Years
Source: ClinicalTrials.gov · Last updated 18 Mar 2025
Brief summary (registry, in English)
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis. Heart rate fluctuations are highly dependent on ANS control, making the heart one of the best indicators of ANS activity. Low ANS activity level is associated with severe cardiac and cerebral events, as well as to death from any cause in the general population. It is even associated with sleep apnea/hypopnea.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 852 (actual)
- First submitted
- 3 Oct 2008
- Start date
- 15 Jan 2003
- Primary completion date
- Dec 2026
- Lead sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Diseases
- Stroke
- NCT number
- NCT00766584
What you commit to
- Study type: Observational
- Participants enrolled: 852
- From 15 Jan 2003 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- prior myocardiac infarction
- prior stroke
Other illness
- hearth failure
- insulin-treated diabetes mellitus
- cardiac pacemaker
- respiratory failure with oxygenotherapy
- sleep-related breathing disorders known and treated
Age
- disease limiting life expectancy to \< 5 years
Other
- atrial fibrillation
- contraindication to brain MRI
- living in an institution
Who the study is looking for
- informed consent signed
- to participate in the PROOF study
Age in the registry: 67 years to 68 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier de Saint-Etienne Coordinator of this site? Confirm its status | Saint-Etienne | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.