NCT00796146Recruiting
Establish and Characterize an Acute HIV Infection Cohort in a High Risk Population
Source: ClinicalTrials.gov · Last updated 27 Apr 2026
Brief summary (registry, in English)
To describe clinical, immunological, and virological characteristics of persons with acute HIV infection 1. To describe demographics and behavioral risk factors for those identified with acute HIV infection 2. To describe neurocognitive function and neuroimaging findings in acute HIV infection as well as describe immune response, HIV-1 genotypes and sequences in the cerebrospinal fluid. 3. To describe the number and characteristics of sexual contacts 4. To describe the willingness of acute HIV-infected subjects to allow the tracking of their sexual contacts for voluntary HIV counseling and testing (VCT) 5. To describe immune response, HIV-1 genotypes and sequences in the genital compartment 6. To describe T cell depletion in the gut mucosa in acute HIV infection and describe the changes in gut T cell during follow up 7. To archive samples for future investigations including determination of viral evolution, and cell-mediated and humoral immune responses in peripheral blood and mucosal compartments
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 777 (estimated)
- First submitted
- 21 Nov 2008
- Start date
- Apr 2009
- Primary completion date
- Jul 2033
- Lead sponsor
- SEARCH Research Foundation
- Diseases
- HIV
- NCT number
- NCT00796146
What you commit to
- Study type: Observational
- Planned participants: 777
- From Apr 2009 to the primary completion date, Jul 2033
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Persons who have a history of a medical or psychiatric disorder by investigator's interview and physical examination according to standard practices, that in the judgment of the investigator(s), would interfere with or serve as a contraindication to adherence to the study protocol or ability to give informed consent.
Other
- Female participants who are pregnant at the time of screening
Who the study is looking for
- Age \>18 years old
- Have protocol-defined acute HIV-1 infection (Tested 4th generation HIV EIA negative and NAT positive or tested 4th generation HIV EIA positive, negative by less sensitive EIA and NAT positive)
- Understand the study and sign informed consent form. Persons who cannot read will have the consent form read to them by a study staff and they can give informed consent by using thumb print.
- Availability for follow-up for the planned study duration
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institute of HIV Research and Innovation (IHRI) Coordinator of this site? Confirm its status | Bangkok | Thailand | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.