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NCT00856947Active, not recruitingPhase 1

Vitamin D Supplementation During Pregnancy for Prevention of Asthma in Childhood

Vitamin D Supplementation During Pregnancy for Prevention of Asthma in Childhood: An Interventional Trial in the ABC (Asthma Begins in Childhood) Cohort

Source: ClinicalTrials.gov · Last updated 19 Mar 2026

Brief summary (registry, in English)

The aim of this study is to prevent asthma symptoms (recurrent wheeze) in childhood by supplementation with high dose vitamin D to the mother during pregnancy. Participants are mothers and children of the ABC (Asthma Begins in Childhood) cohort. Mothers are recruited during pregnancy and receive daily supplement with 2400 IU of Vitamin D3 or placebo from week 24 og gestation to 1 week after delivery. In addition all mothers are advised to take the recommended dose of 400 IU vitamin D daily. The mothers in ABC also participate in an interventional trial with fish oil supplementation, and the vitamin D randomization is stratified by fish oil treatment group. The child is followed with acute and planned vits at the research unit, and wheeze is diagnosed according to predefined algorithms.

Status (registry)
Active, not recruiting
Phase (registry)
Phase 1
Study type
Interventional
Enrollment
600 (estimated)
First submitted
4 Mar 2009
Start date
Mar 2009
Primary completion date
Jul 2027
Lead sponsor
Copenhagen Studies on Asthma in Childhood
NCT number
NCT00856947

What you commit to

  • Study type: Interventional · Phase 1
  • Planned participants: 600
  • From Mar 2009 to the primary completion date, Jul 2027
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Tuberculosis

Lab values

  • Endocrinological disease such as calcium metabolic disorder, parathyroid disorder, thyroid disorder or Diabetes type 1
  • In need of diuretics or heart medication including calcium channel blockers

Other

  • Mother:
  • Intake of more than 400 IU of vitamin D during the last 6 months
  • Sarcoidosis

Who the study is looking for

  • Mother:
  • Pregnant in week 22-26 of gestation
  • Participating in the ABC-cohort
  • Living in Sealand, Denmark
  • Fluent in Danish
  • Willing to let the child participate in the study

Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Copenhagen University Hospital of Copenhagen
Coordinator of this site? Confirm its status		Gentofte MunicipalityDenmarkUnknown status
Næstved Hospital, Pediatric Department
Coordinator of this site? Confirm its status		NæstvedDenmarkUnknown status

Related publications

This page is information, not medical advice. Discuss any trial with your doctor.