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NCT00957450Active, not recruiting

Intra-Pelvic Organ Motion for Cervix Cancer Patient Using Imaging

Validation Study of Modeled Intra-pelvic Organ Motion During External Beam Radiotherapy for Cervix Cancer Using Frequent Magnetic Resonance Imaging

Source: ClinicalTrials.gov · Last updated 6 Mar 2026

Brief summary (registry, in English)

Patients with cervix cancer having radiotherapy experience side-effects because the radiotherapy fields have to be quite large to account for tumour movement in the pelvis during treatment, this irradiates a lot of normal tissues. This study aims to characterize and model the tumour motion, as well as the motion of surrounding normal tissues, during treatment. By doing this, the investigators can look at ways to minimise tumour motion and spare more normal tissues. By tailoring the radiotherapy dose more accurately, the investigators will reduce the side-effects of treatment and improve local control of the tumour. By doing multiple magnetic resonance imaging (MRI) scans of the patients during treatment, the investigators can identify where the tumour and surrounding normal tissues are at that point in time. Collecting all the information from these scans, will allow the investigators to model the motion of the tumour and these pelvic organs, and investigate the best way to target the tumour while still sparing normal tissues.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
12 (actual)
First submitted
11 Aug 2009
Start date
Feb 2008
Primary completion date
Feb 2029
Lead sponsor
University Health Network, Toronto
NCT number
NCT00957450

What you commit to

  • Study type: Observational
  • Participants enrolled: 12
  • From Feb 2008 to the primary completion date, Feb 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Prior pelvic radiotherapy

Other

  • Patients unwilling or unable to give informed consent
  • Contraindications to MRI scan

Who the study is looking for

  • Age ≥ 18years
  • Biopsy confirmed cervix cancer
  • Not suitable for surgery
  • Suitable for radical radiotherapy
  • ECOG 0-2
  • Informed consent

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Health Network
Coordinator of this site? Confirm its status
TorontoCanadaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.