NCT01005485Active, not recruiting
Molecular and Morphologic Characterization of Circulating Endothelial Cells
Comprehensive Molecular and Morphologic Characterization of Circulating Endothelial Cells
Source: ClinicalTrials.gov · Last updated 17 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The primary hypothesis of this study is that circulating endothelial cells (CECs) harbor key genetic and structural characteristics predisposing individuals to acute atherosclerotic plaque rupture and heart attack.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 664 (actual)
- First submitted
- 29 Oct 2009
- Start date
- 1 Jan 2010
- Primary completion date
- 30 Apr 2017
- Lead sponsor
- Scripps Translational Science Institute
- Diseases
- Coronary artery disease
- NCT number
- NCT01005485
What you commit to
- Study type: Observational
- Participants enrolled: 664
- From 1 Jan 2010 to the primary completion date, 30 Apr 2017
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous history of coronary artery disease or MI
Other illness
- 1\. Has a significant medical condition that in the investigator's opinion may interfere with the patient's optimal participation in the study.
- Diabetes
- Peripheral arterial disease
- Hypertension (\>140/90 or on blood pressure medication)
- Sickle cell disease
- Acute or Chronic kidney disease
- Acute or Chronic vascular conditions, not otherwise specified
- Active or history of inflammation of connective tissue and vascular structures (i.e. vasculitis, rheumatoid arthritis)
Age
- Age greater than 35
Other
- General Exclusion Criteria:
- Exclusion for Healthy Controls:
Who the study is looking for
- Age 18 - 80 years old.
- Must be reliable, cooperative and willing to comply with all protocol-specified procedures if consented.
- Able to understand and grant informed consent
- Subjects must meet one of the following (a-c):
- Healthy control subjects not meeting any exclusion criteria for controls below
- Patients scheduled for an open vascular procedure of an arterial structure
- Patients with acute MI defined as:
- Clinical history and symptoms consistent with acute MI AND ii Elevated cardiac markers (CKMB, Troponin I or T) consistent with MI (abnormals are according to enrolling institution's lab standards) AND iii. Able to complete study enrollment (consent \& blood draw) within 48 hours of presentation to the study site.
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Scrippshealth Coordinator of this site? Confirm its status | La Jolla | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.