NCT01044160Active, not recruiting
Stress, Adjustment And Growth In Children With Cancer And Their Parents
Source: ClinicalTrials.gov · Last updated 24 Aug 2026
Brief summary (registry, in English)
This proposal examines trauma and growth responses in the childhood cancer experience. It addresses a number of gaps and unanswered questions in the literature, while integrating several distinct but related lines of research. The rationale for this proposal is outlined briefly as follows: 1. Traumatic stress models focused on pathology dominate pediatric psychosocial oncology research despite empiric evidence of low levels of post-traumatic stress in this population. 2. The assumption of 'cancer as a traumatic event' has biased research designs (including lack of control comparisons) to focus on deficits and pathological outcomes. 3. This deficit-oriented approach has stimulated the development of interventions to treat or prevent PTSD, which may be unnecessary or even harmful. 4. Theoretical and empiric evidence suggests that a more common response to traumatic stress is growth and positive change, but posttraumatic growth phenomenon have been understudied in pediatric populations. 5. Cognitive and personality factors are important determinants of PTSD and positive growth outcomes, and some constructs from positive psychology theory may be particularly relevant in children with cancer. 6. Empirically, parents of children with cancer appear to be at higher risk of PTSD/PTSS, although results are not unequivocal, and the same research biases have applied to parental outcomes. This proposal includes assessment of parental PTSS and PTG, both as an outcome and a predictor of child outcomes.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 663 (actual)
- First submitted
- 5 Jan 2010
- Start date
- 7 Jul 2009
- Primary completion date
- 30 Apr 2029
- Lead sponsor
- St. Jude Children's Research Hospital
- Diseases
- Childhood cancers
- NCT number
- NCT01044160
What you commit to
- Study type: Observational
- Participants enrolled: 663
- From 7 Jul 2009 to the primary completion date, 30 Apr 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Primary Group
- Research participant is 8-17 years inclusive
- Research participant has a primary diagnosis of malignancy
- Research participant is at least one month from diagnosis with no upper limit in terms of time elapsed since diagnosis;
- Research participant is able to speak and read English;
- Research participant does not have any significant cognitive or sensory deficits that would preclude participation;
- Parent/LAR and research participant is willing to participate and provide consent/assent
- Young Child Group
- Research participant is 3 - 6 years of age, inclusive
- Primary diagnosis of malignancy
- At least one month from diagnosis
- One parent/LAR willing to participate and provide consent
- No history of sensory or developmental disorder that would invalidate study assessment procedures.
- Young Adult Group
- Research participant is 18-25 years of age inclusive
- Primary diagnosis of malignancy
- At least one month from diagnosis with no upper limit in terms of time elapsed from diagnosis
- Able to read and speak English
- No cognitive or sensory deficits that would preclude participation
- Willing to participate and provide consent
- Control Groups
- Research participant in 3 age groups (3 - 6 years; 8-17 years; 18-25 years) to match patient groups
- No history of chronic or life-threatening illness
- No cognitive or sensory impairment that would preclude completion of study measures
- Able to speak and read English
- Parent/LAR and research participant are willing to participate and provide informed consent/assent
- Exclusions Criteria:NA
Age in the registry: 3 years to 25 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. Jude Children's Research Hospital Coordinator of this site? Confirm its status | Memphis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.